clinical trials

Utility of the number needed to treat in paediatric haematological cancer randomised controlled treatment trials: a systematic review
Haroon Hasan, Karen Goddard, A Fuchsia Howard

BMJ Open Feb 2019, 9 (2) e022839; DOI: 10.1136/bmjopen-2018-022839
Cost-effectiveness of cell salvage and donor blood transfusion during caesarean section: results from a randomised controlled trial
Carol McLoughlin, Tracy E Roberts, Louise J Jackson, Philip Moore, Matthew Wilson, Richard Hooper, Shubha Allard, Ian Wrench, Lee Beresford, James Geoghegan, Jane Daniels, Sue Catling, Vicki A Clark, Paul Ayuk, Stephen Robson, Fang Gao-Smith, Matthew Hogg, Doris Lanz, Julie Dodds, Khalid S Khan

BMJ Open Feb 2019, 9 (2) e022352; DOI: 10.1136/bmjopen-2018-022352
Tramadol/dexketoprofen (TRAM/DKP) compared with tramadol/paracetamol in moderate to severe acute pain: results of a randomised, double-blind, placebo and active-controlled, parallel group trial in the impacted third molar extraction pain model (DAVID study)
Cosme Gay-Escoda, Magdi Hanna, Antonio Montero, Thomas Dietrich, Stefano Milleri, Ewa Giergiel, Tóth Bagi Zoltán, Giustino Varassi

BMJ Open Feb 2019, 9 (2) e023715; DOI: 10.1136/bmjopen-2018-023715
SAFETEL randomised controlled feasibility trial of a safety planning intervention with follow-up telephone contact to reduce suicidal behaviour: study protocol
Rory C O’Connor, Jenna-Marie Lundy, Corinna Stewart, Susie Smillie, Heather McClelland, Suzy Syrett, Marcela Gavigan, Alex McConnachie, Michael Smith, Daniel J Smith, Gregory K Brown, Barbara Stanley, Sharon Anne Simpson

BMJ Open Feb 2019, 9 (2) e025591; DOI: 10.1136/bmjopen-2018-025591
Internet delivery of intensive speech and language therapy for children with cerebral palsy: a pilot randomised controlled trial
Lindsay Pennington, Elaine Stamp, Johanna Smith, Helen Kelly, Naomi Parker, Katy Stockwell, Patricia Aluko, Mohammad Othman, Katie Brittain, Luke Vale

BMJ Open Jan 2019, 9 (1) e024233; DOI: 10.1136/bmjopen-2018-024233
Prevention of child mental health problems in Southeastern Europe: a multicentre sequential study to adapt, optimise and test the parenting programme ‘Parenting for Lifelong Health for Young Children’, protocol for stage 1, the feasibility study
Inga Frantz, Heather M Foran, Jamie M Lachman, Elena Jansen, Judy Hutchings, Adriana Băban, Xiangming Fang, Frances Gardner, Galina Lesco, Marija Raleva, Catherine L Ward, Margiad Elen Williams, Nina Heinrichs

BMJ Open Jan 2019, 9 (1) e026684; DOI: 10.1136/bmjopen-2018-026684
Adjuvant rituximab, a potential treatment for the young patient with Graves’ hyperthyroidism (RiGD): study protocol for a single-arm, single-stage, phase II trial
Michael Cole, Ann Marie Hynes, Denise Howel, Lesley Hall, Mario Abinun, Amit Allahabadia, Timothy Barrett, Kristien Boelaert, Amanda J Drake, Paul Dimitri, Jeremy Kirk, Nicola Zammitt, Simon Pearce, Tim Cheetham

BMJ Open Jan 2019, 9 (1) e024705; DOI: 10.1136/bmjopen-2018-024705
Supporting children and young people when making decisions about joining clinical trials: qualitative study to inform multimedia website development
Jacqueline M Martin-Kerry, Peter Knapp, Karl Atkin, Peter Bower, Ian Watt, Catherine Stones, Steven Higgins, Rebecca Sheridan, Jenny Preston, Danielle Horton Taylor, Paul Baines, Bridget Young

BMJ Open Jan 2019, 9 (1) e023984; DOI: 10.1136/bmjopen-2018-023984
Randomised controlled study comparing general and spinal anaesthesia with and without a tourniquet on the outcomes of total knee arthroplasty: study protocol
Mikko Tuomas Rantasalo, Riku Palanne, Katarina Juutilainen, Pekka Kairaluoma, Rita Linko, Elina Reponen, Teemu Helkamaa, Anne Vakkuri, Klaus T Olkkola, Rami Madanat, Noora Kati Annukka Skants

BMJ Open Dec 2018, 8 (12) e025546; DOI: 10.1136/bmjopen-2018-025546
Selective carious tissue removal using subjective criteria or polymer bur: study protocol for a randomised controlled trial (SelecCT)
Falk Schwendicke, Soraya Leal, Peter Schlattmann, Sebastian Paris, Ana Paula Dias Ribeiro, Marta Gomes Marques, Leandro Augusto Hilgert

BMJ Open Dec 2018, 8 (12) e022952; DOI: 10.1136/bmjopen-2018-022952

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