clinical trials

Protocol for a randomised trial of an interprofessional team-delivered intervention to support surrogate decision-makers in ICUs
Taylor Lincoln, Anne-Marie Shields, Praewpannarai Buddadhumaruk, Chung-Chou H Chang, Francis Pike, Hsiangyu Chen, Elke Brown, Veronica Kozar, Caroline Pidro, Jeremy M Kahn, Joseph M Darby, Susan Martin, Derek C Angus, Robert M Arnold, Douglas B White

BMJ Open Mar 2020, 10 (3) e033521; DOI: 10.1136/bmjopen-2019-033521
Cognitive–behavioural group therapy for adolescents with ADHD: study protocol for a randomised controlled trial
Torunn Stene Nøvik, Anne-Lise Juul Haugan, Stian Lydersen, Per Hove Thomsen, Susan Young, Anne Mari Sund

BMJ Open Mar 2020, 10 (3) e032839; DOI: 10.1136/bmjopen-2019-032839
Validating the effect of Ondansetron and Mirtazapine In Treating hyperemesis gravidarum (VOMIT): protocol for a randomised placebo-controlled trial
Anne Ostenfeld, Tonny Studsgaard Petersen, Tina Bergmann Futtrup, Jon Trærup Andersen, Andreas Kryger Jensen, Hanne Brix Westergaard, Lars Henning Pedersen, Ellen Christine Leth Løkkegaard

BMJ Open Mar 2020, 10 (3) e034712; DOI: 10.1136/bmjopen-2019-034712
PREDICtors for health-related quality of life after elective sigmoidectomy for DIVerticular disease: the PREDIC-DIV study protocol of a prospective multicentric transnational observational study
Maximilian Sohn, Ayman Agha, Igors Iesalnieks, Susanne Bremer, Stefanie Trum, Francesca Di Cerbo, Andreas Nerlich, Natalie Lotz, Eckhard Klieser, Alfred Hochrein, Philipp Schredl, Dariya Kalcheva, Klaus Emmanuel, Jaroslav Presl

BMJ Open Mar 2020, 10 (3) e034385; DOI: 10.1136/bmjopen-2019-034385
What are potential barriers and enablers to patient and physician participation in Canadian cell therapy trials for stroke? A stakeholder interview study
Manoj M Lalu, Madison Foster, Justin Presseau, Dar Dowlatshahi, Gisell Castillo, Analyssa Cardenas, Whitney Tam, Jennifer Zlepnig, Deborah Timpson, Yuan Yi Dong, Pascale Juneau, Dean A Fergusson

BMJ Open Mar 2020, 10 (3) e034354; DOI: 10.1136/bmjopen-2019-034354
Outcome reporting bias in Cochrane systematic reviews: a cross-sectional analysis
Kieran Shah, Gregory Egan, Lawrence (Nichoe) Huan, Jamie Kirkham, Emma Reid, Aaron M Tejani

BMJ Open Mar 2020, 10 (3) e032497; DOI: 10.1136/bmjopen-2019-032497
Study protocol of a randomised controlled trial of prostate radiotherapy in high-risk and node-positive disease comparing moderate and extreme hypofractionation (PRIME TRIAL)
Vedang Murthy, Indranil Mallick, Abhilash Gavarraju, Shwetabh Sinha, Rahul Krishnatry, Tejshri Telkhade, Arunsingh Moses, Sadhna Kannan, Gagan Prakash, Mahendra Pal, Santosh Menon, Palak Popat, Venkatesh Rangarajan, Archi Agarwal, Sheetal Kulkarni, Ganesh Bakshi

BMJ Open Feb 2020, 10 (2) e034623; DOI: 10.1136/bmjopen-2019-034623
Tackling frailty at primary care: evaluation of the effectiveness of a multicomponent intervention through a randomised controlled trial: study protocol
Francisco Rivas-Ruiz, Mónica Machón, Maider Mateo-Abad, Eugenio Contreras-Fernández, Carolina Güell, Luis Baro-Rodríguez, Kalliopi Vrotsou, Raúl Quirós-López, Itziar Vergara

BMJ Open Feb 2020, 10 (2) e034591; DOI: 10.1136/bmjopen-2019-034591
Improving reproductive function in women with polycystic ovary syndrome with high-intensity interval training (IMPROV-IT): study protocol for a two-centre, three-armed randomised controlled trial
Ida Almenning Kiel, Sofie Lionett, Evelyn Bridget Parr, Helen Jones, Maria Aurora Hernandez Røset, Øyvind Salvesen, Eszter Vanky, Trine Moholdt

BMJ Open Feb 2020, 10 (2) e034733; DOI: 10.1136/bmjopen-2019-034733
Efficacy and safety of a supplement combination for hand osteoarthritis pain: protocol for an internet-based randomised placebo-controlled trial (The RADIANT study)
Xiaoqian Liu, Sarah Robbins, Jillian Eyles, Tatyana Fedorova, Sonika Virk, Leticia A Deveza, Andrew McLachlan, David Hunter

BMJ Open Feb 2020, 10 (2) e035672; DOI: 10.1136/bmjopen-2019-035672

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