Clinical Pharmacology

Severity of coeliac disease and clinical management study when using a CYP3A4 metabolised medication: a phase I pharmacokinetic study
Marc L Chretien, David G Bailey, Linda Asher, Jeremy Parfitt, David Driman, Jamie Gregor, George K Dresser

BMJ Open Mar 2020, 10 (3) e034086; DOI: 10.1136/bmjopen-2019-034086
Pharmacist-led intervention to improve medication use in older inpatients using the Drug Burden Index: a study protocol for a before/after intervention with a retrospective control group and multiple case analysis
Marci Elizabeth Dearing, Susan Bowles, Jennifer Isenor, Olga Kits, Lisa Kouladjian O'Donnell, Heather Neville, Sarah Hilmer, Kent Toombs, Caroline Sirois, Mohammad Hajizadeh, Aprill Negus, Kenneth Rockwood, Emily Reeve

BMJ Open Feb 2020, 10 (2) e035656; DOI: 10.1136/bmjopen-2019-035656
Atorvastatin for prevention of disease progression and hospitalisation in liver cirrhosis: protocol for a randomised, double-blind, placebo-controlled trial
Nina Kimer, Henning Grønbæk, Rikard Gøran Fred, Torben Hansen, Atul Shahaji Deshmukh, Mathias Mann, Flemming Bendtsen

BMJ Open Jan 2020, 10 (1) e035284; DOI: 10.1136/bmjopen-2019-035284
Randomised, double-blind, placebo-controlled clinical trial investigating the effects of inorganic nitrate in hypertension-induced target organ damage: protocol of the NITRATE-TOD study in the UK
Clement Wai Zhen Lau, Alexander Jozua Pedro Hamers, Krishnaraj Sinhji Rathod, Asad Shabbir, Jackie Cooper, Christopher Peter Primus, Ceri Davies, Anthony Mathur, James C Moon, Vikas Kapil, Amrita Ahluwalia

BMJ Open Jan 2020, 10 (1) e034399; DOI: 10.1136/bmjopen-2019-034399
Application of a Common Data Model (CDM) to rank the paediatric user and prescription prevalence of 15 different drug classes in South Korea, Hong Kong, Taiwan, Japan and Australia: an observational, descriptive study
Ruth Brauer, Ian Chi Kei Wong, Kenneth KC Man, Nicole L Pratt, Rae Woong Park, Soo-Yeon Cho, Yu-Chuan (Jack) Li, Usman Iqbal, Phung-Anh Alex Nguyen, Martijn Schuemie

BMJ Open Jan 2020, 10 (1) e032426; DOI: 10.1136/bmjopen-2019-032426
Cannabinoids versus placebo or no intervention for pain: protocol for a systematic review with meta-analysis and trial sequential analysis
Jehad Ahmad Barakji, Steven Kwasi Korang, Joshua Feinberg, Mathias Maagard, Christian Gluud, Ole Mathiesen, Janus Christian Jakobsen

BMJ Open Oct 2019, 9 (10) e031574; DOI: 10.1136/bmjopen-2019-031574
Effect of dose administration aids on adherence to self-administered medications: a systematic review protocol
Kanika Chaudhri, Madeleine Kearney, Richard O Day, Anthony Rodgers, Emily Atkins

BMJ Open Oct 2019, 9 (10) e030536; DOI: 10.1136/bmjopen-2019-030536
Pharmacological interventions for the prevention of fetal growth restriction: protocol for a systematic review and network meta-analysis
Alessandra Bettiol, Niccolò Lombardi, Giada Crescioli, Laura Avagliano, Alessandro Mugelli, Claudia Ravaldi, Alfredo Vannacci

BMJ Open Jul 2019, 9 (7) e029467; DOI: 10.1136/bmjopen-2019-029467
Using prescribing very short answer questions to identify sources of medication errors: a prospective study in two UK medical schools
Amir H Sam, Chee Yeen Fung, Rebecca K Wilson, Emilia Peleva, David C Kluth, Martin Lupton, David R Owen, Colin R Melville, Karim Meeran

BMJ Open Jul 2019, 9 (7) e028863; DOI: 10.1136/bmjopen-2018-028863
Rationale and design of OPtimising thERapy to prevent Avoidable hospital admissions in Multimorbid older people (OPERAM): a cluster randomised controlled trial
Luise Adam, Elisavet Moutzouri, Christine Baumgartner, Axel Lennart Loewe, Martin Feller, Khadija M’Rabet-Bensalah, Nathalie Schwab, Stefanie Hossmann, Claudio Schneider, Sabrina Jegerlehner, Carmen Floriani, Andreas Limacher, Katharina Tabea Jungo, Corlina Johanna Alida Huibers, Sven Streit, Matthias Schwenkglenks, Marco Spruit, Anette Van Dorland, Jacques Donzé, Patricia M Kearney, Peter Jüni, Drahomir Aujesky, Paul Jansen, Benoit Boland, Olivia Dalleur, Stephen Byrne, Wilma Knol, Anne Spinewine, Denis O’Mahony, Sven Trelle, Nicolas Rodondi

BMJ Open Jun 2019, 9 (6) e026769; DOI: 10.1136/bmjopen-2018-026769

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