Clinical Pharmacology

Study protocol for a single-centre, prospective, non-blinded, randomised, 12-month, parallel-group superiority study to compare the efficacy of pharmacist intervention versus usual care for elderly patients hospitalised in orthopaedic wards
Junpei Komagamine, Kenichi Sugawara, Miho Kaminaga, Shinpei Tatsumi

BMJ Open Jul 2018, 8 (7) e021924; DOI: 10.1136/bmjopen-2018-021924
Does glucagon-like peptide-1 (GLP-1) receptor agonist stimulation reduce alcohol intake in patients with alcohol dependence: study protocol of a randomised, double-blinded, placebo-controlled clinical trial
Kerstin K Antonsen, Mette K Klausen, Amanda S Brunchmann, Nina le Dous, Mathias E Jensen, Kamilla Woznica Miskowiak, Patrick M Fisher, Gerda K Thomsen, Henrik Rindom, Thomas P Fahmy, Sabine Vollstaedt-Klein, Helene Benveniste, Nora D Volkow, Ulrik Becker, Claus Ekstrøm, Gitte Moos Knudsen, Tina Vilsbøll, Anders Fink-Jensen

BMJ Open Jul 2018, 8 (7) e019562; DOI: 10.1136/bmjopen-2017-019562
Treatment and persistence with oral anticoagulants among newly diagnosed patients with non-valvular atrial fibrillation: a retrospective observational study in a US commercially insured and Medicare Advantage population
Vincent Willey, Jessica Franchino-Elder, An-Chen Fu, Cheng Wang, Stephen Sander, Hiangkiat Tan, Elizabeth Kraft, Rahul Jain

BMJ Open Jun 2018, 8 (6) e020676; DOI: 10.1136/bmjopen-2017-020676
Impact of body weight, low energy diet and gastric bypass on drug bioavailability, cardiovascular risk factors and metabolic biomarkers: protocol for an open, non-randomised, three-armed single centre study (COCKTAIL)
Jøran Hjelmesæth, Anders Åsberg, Shalini Andersson, Rune Sandbu, Ida Robertsen, Line Kristin Johnson, Philip Carlo Angeles, Jens Kristoffer Hertel, Eva Skovlund, Maria Heijer, Anna-Lena Ek, Veronica Krogstad, Tor-Ivar Karlsen, Hege Christensen, Tommy B Andersson, Cecilia Karlsson

BMJ Open May 2018, 8 (5) e021878; DOI: 10.1136/bmjopen-2018-021878
Development and evaluation of an algorithm-based tool for Medication Management in nursing homes: the AMBER study protocol
Susanne Erzkamp, Olaf Rose

BMJ Open Apr 2018, 8 (4) e019398; DOI: 10.1136/bmjopen-2017-019398
Antithrombotic therapy in patients receiving saphenous vein coronary artery bypass grafts: a protocol for a systematic review and network meta-analysis
Karla Solo, Janet Martin, Shahar Lavi, Conrad Kabali, Ava John-Baptiste, Immaculate F Nevis, Tawfiq Choudhury, Mamas A Mamas, Rodrigo Bagur

BMJ Open Apr 2018, 8 (4) e019555; DOI: 10.1136/bmjopen-2017-019555
Dabigatran persistence and adherence in New Zealand: a nationwide retrospective observational study
Paul Harper, Daryl Pollock, Matt Stephens

BMJ Open Apr 2018, 8 (4) e020212; DOI: 10.1136/bmjopen-2017-020212
Real-world effects of medications for chronic obstructive pulmonary disease: protocol for a UK population-based non-interventional cohort study with validation against randomised trial results
Kevin Wing, Elizabeth Williamson, James R Carpenter, Lesley Wise, Sebastian Schneeweiss, Liam Smeeth, Jennifer K Quint, Ian Douglas

BMJ Open Mar 2018, 8 (3) e019475; DOI: 10.1136/bmjopen-2017-019475
Effect of an increased dosage of statins on spinal degenerative joint disease: a retrospective cohort study
Yuan-Yang Cheng, Chung-Lan Kao, Shih-Yi Lin, Shin-Tsu Chang, Tz-Shiang Wei, Shih-Ni Chang, Ching-Heng Lin

BMJ Open Feb 2018, 8 (2) e017442; DOI: 10.1136/bmjopen-2017-017442
Evaluating the impact of type 2 diabetes mellitus on CYP450 metabolic activities: protocol for a case–control pharmacokinetic study
Sophie Gravel, Jean-Louis Chiasson, Suzanne Dallaire, Jacques Turgeon, Veronique Michaud

BMJ Open Feb 2018, 8 (2) e020922; DOI: 10.1136/bmjopen-2017-020922

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