Chemotherapy

Cytoreductive surgery (CRS) with hyperthermic intraoperative peritoneal chemotherapy (HIPEC) versus standard of care (SoC) in people with peritoneal metastases from colorectal, ovarian or gastric origin: protocol for a systematic review and individual participant data (IPD) meta-analyses of effectiveness and cost-effectiveness
Kurinchi Gurusamy, Claire L Vale, Elena Pizzo, R Bhanot, Brian R Davidson, Tim Mould, Muntzer Mughal, Mark Saunders, Omer Aziz, Sarah O'Dwyer

BMJ Open May 2020, 10 (5) e039314; DOI: 10.1136/bmjopen-2020-039314
Association between multiple symptoms and quality of life of paediatric patients with cancer in Brazil: a cross-sectional study
Sandra de Andrade Cadamuro, Julia Onishi Franco, Carlos Eduardo Paiva, Marco Antonio de Oliveira, Bianca Sakamoto Ribeiro Paiva

BMJ Open May 2020, 10 (5) e035844; DOI: 10.1136/bmjopen-2019-035844
Cost-effectiveness analysis of cetuximab combined with chemotherapy as a first-line treatment for patients with RAS wild-type metastatic colorectal cancer based on the TAILOR trial
Huijuan Wang, Lingfei Huang, Peng Gao, Zhengyi Zhu, Weifeng Ye, Haiying Ding, Luo Fang

BMJ Open Feb 2020, 10 (2) e030738; DOI: 10.1136/bmjopen-2019-030738
Cost-effectiveness analysis of pembrolizumab plus chemotherapy for previously untreated metastatic non-small cell lung cancer in the USA
Xiaohui Zeng, Xiaomin Wan, Liubao Peng, Ye Peng, Fang Ma, Qiao Liu, Chongqing Tan

BMJ Open Dec 2019, 9 (12) e031019; DOI: 10.1136/bmjopen-2019-031019
Furosemide versus mannitol in Japanese patients with thoracic malignancy who received cisplatin-based chemotherapy using short hydration: study protocol for a randomised controlled trial
Eriko Murakami, Hiroaki Akamatsu, Toshio Shimokawa, Kiyoko Wada, Nobuyuki Yamamoto

BMJ Open Dec 2019, 9 (12) e029057; DOI: 10.1136/bmjopen-2019-029057
Simultaneous resection of the primary tumour and liver metastases after conversion chemotherapy versus standard therapy in pancreatic cancer with liver oligometastasis: protocol of a multicentre, prospective, randomised phase III control trial (CSPAC-1)
Miaoyan Wei, Si Shi, Jie Hua, Jin Xu, Xianjun Yu

BMJ Open Dec 2019, 9 (12) e033452; DOI: 10.1136/bmjopen-2019-033452
Effect of different types of exercise on health-related quality of life during and after cancer treatment: a protocol for a systematic review and network meta-analysis
Esther Ubago-Guisado, Luis Gracia-Marco, Iván Cavero-Redondo, Vicente Martinez-Vizcaino, Blanca Notario-Pacheco, Diana P Pozuelo-Carrascosa, Esther G Adalia, Celia Álvarez-Bueno

BMJ Open Nov 2019, 9 (11) e031374; DOI: 10.1136/bmjopen-2019-031374
Evaluation of the role of transhepatic flow in postoperative outcomes following major hepatectomy (THEFLOW): study protocol for a single-centre, non-interventional cohort study
Mohammad Golriz, Anastasia Lemekhova, Elias Khajeh, Omid Ghamarnejad, Mohammed Al-Saeedi, Oliver Strobel, Thilo Hackert, Beat Müller-Stich, Martin Schneider, Christoph Berchtold, Parham Tinoush, Philipp Mayer, De-Hua Chang, Karl Heinz Weiss, Katrin Hoffmann, Arianeb Mehrabi

BMJ Open Oct 2019, 9 (10) e029618; DOI: 10.1136/bmjopen-2019-029618
Application of orphan drug designation to cancer treatments (2008–2017): a comprehensive and comparative analysis of the USA and EU
Kerstin Noëlle Vokinger, Aaron S Kesselheim

BMJ Open Oct 2019, 9 (10) e028634; DOI: 10.1136/bmjopen-2018-028634
Incidence of cancer-associated thromboembolism in Japanese gastric and colorectal cancer patients receiving chemotherapy: a single-institutional retrospective cohort analysis (Sapporo CAT study)
Ayane Oba Aonuma, Michio Nakamura, Kentaro Sakamaki, Taichi Murai, Chika Matsuda, Kazufumi Itaya, Takayuki Sone, Masataka Yagisawa, Yuta Koike, Ayana Endo, Yoko Tsukuda, Yuji Ono, Atsushi Nagasaka, Shuji Nishikawa, Takeharu Yamanaka, Naoya Sakamoto

BMJ Open Aug 2019, 9 (8) e028563; DOI: 10.1136/bmjopen-2018-028563

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