bleeding disorders & coagulopathies

Exploration of the impact of gene therapy on the lives of people with haemophilia and their families: a protocol for the mixed-methods exigency study
Simon Fletcher, Luke Pembroke, Mike Holland, Kate Khair

BMJ Open Aug 2022, 12 (8) e060351; DOI: 10.1136/bmjopen-2021-060351
Economic evaluation of tranexamic acid for the treatment of acute gastrointestinal bleeding: a cost-effectiveness analysis using data from the HALT-IT randomised controlled trial
Nuha Bazeer, Alec Miners, Ian Roberts, Haleema Shakur-Still, Vipul Jairath, Jack Williams

BMJ Open Jul 2022, 12 (7) e060505; DOI: 10.1136/bmjopen-2021-060505
Exploring the epidemiology of disseminated intravascular coagulation: protocol for the DANish Disseminated Intravascular Coagulation (DANDIC) Cohort Study
Simon Flæng, Søren Nygaard, Asger Granfeldt, Anne-Mette Hvas, Henrik Toft Sørensen, Jecko Thachil, Kasper Adelborg

BMJ Open Jul 2022, 12 (7) e062623; DOI: 10.1136/bmjopen-2022-062623
Detection of exhaled methane levels for monitoring trauma-related haemorrhage following blunt trauma: study protocol for a prospective observational study
Péter Jávor, Ferenc Rárosi, Tamara Horváth, László Török, Endre Varga, Petra Hartmann

BMJ Open Jul 2022, 12 (7) e057872; DOI: 10.1136/bmjopen-2021-057872
Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study
Mei Wang, Michael Paterson, Lehana Thabane, Deborah Siegal, Lawrence Mbuagbaw, Laura Targownik, Anne Holbrook

BMJ Open Jun 2022, 12 (6) e057991; DOI: 10.1136/bmjopen-2021-057991
Safety and effectiveness of appropriately and inappropriately dosed rivaroxaban or apixaban versus warfarin in patients with atrial fibrillation: a cohort study with nested case–control analyses from UK primary care
Antonio González-Pérez, Luke Roberts, Pareen Vora, Maria Eugenia Saez, Gunnar Brobert, Samuel Fatoba, Luis Alberto García Rodríguez

BMJ Open Jun 2022, 12 (6) e059311; DOI: 10.1136/bmjopen-2021-059311
Fibrinogen Early In Severe paediatric Trauma studY (FEISTY junior): protocol for a randomised controlled trial
Shane George, Elizabeth Wake, Melanie Jansen, John Roy, Sharon Maconachie, Anni Paasilahti, Greg Wiseman, Kristen Gibbons, James Winearls

BMJ Open May 2022, 12 (5) e057780; DOI: 10.1136/bmjopen-2021-057780
Association between platelets and in-hospital mortality in critically ill patients with tumours: a retrospective cohort study
Chaofen Zhao, Zuoan Qin, Yaxue Tang, Lina Liu, Yuanyuan Li, Qianyong He, Jieqing Jiang, Yue Chen, Yuxin Li, Shaoyuan Zhu, Xinyu Xu, Ding’an Zhou, Feng Jin

BMJ Open Apr 2022, 12 (4) e053691; DOI: 10.1136/bmjopen-2021-053691
AKATSUKI study: a prospective, multicentre, phase IV study evaluating the safety of emicizumab under and immediately after immune tolerance induction therapy in persons with congenital haemophilia A with factor VIII inhibitors
Tadashi Matsushita, Nobuaki Suzuki, Azusa Nagao, Chiai Nagae, Haruko Yamaguchi-Suita, Yui Kyogoku, Akiko Ioka, Keiji Nogami

BMJ Open Mar 2022, 12 (3) e057018; DOI: 10.1136/bmjopen-2021-057018
Assessment of global coagulation function under treatment with emicizumab concomitantly with bypassing agents in haemophilia A with inhibitor (UNEBI Study): multicentre open-label non-randomised clinical trial
Kenichi Ogiwara, Masashi Taki, Takashi Suzuki, Hideyuki Takedani, Tadashi Matsushita, Kagehiro Amano, Masanori Matsumoto, Kenji Nishio, Midori Shima, Masato Kasahara, Keiji Nogami

BMJ Open Feb 2022, 12 (2) e056922; DOI: 10.1136/bmjopen-2021-056922

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