Table 1

Studies and their characteristics

Asymptomatic CADMI
StudyLocationMale (%)Mean ageIschaemic eventMethod of investigationNnPer cent>50% stenosisnPer cent
Gongora-Rivera et al,23 MASSFrance5560Fatal strokeAutopsy: plaque, ischaemia, MI necrosis/fibrosis >1 cm18813170295931
Amarenco et al,24 AMISTADFrance7262StrokeCoronary angiography3151956226
Ahn et al25Korea6566Stroke/TIACTCA3141454646
Calvet et al,5 PRECORISFrance7063Stroke/TIACTCA2741334918
Cha et al26Korea6463Stroke/TIACTCA173312207033
Cho et al27Korea60681st strokeCTCA2741585822
Hoshino et al28Japan72661st strokeCTCA100363636
Iwasaki et al11Japan6763StrokeCCS (calcium score)151372525
Kim et al29Korea7067StrokeCTCA2001618136
Seo et al30Korea6368StrokeCTCA71182525
Yoon et al31Korea5071Stroke/TIACTCA1751056021
Arauz et al32Mexico69621st strokeStress SPECT1254032
Chimowitz et al33USA6461Stroke/TIAStress thallium myocardial scintigraphy652335
Di Pasquale et al34Italy7356Stroke/TIA of the carotid systemExercise thallium myocardial imaging1403324
Urbinati et al35Italy7164Stroke/TIA of the carotid systemExercise thallium myocardial scintigraphy1212823
Nighoghossian et al10France8059StrokeStress echo60915
Leys et al,36 DETECTFrance7469StrokeECG+echo5636411
Gattringer et al37Austria5374Stroke/TIATroponin+ECG37 2141810.5
Jensen et al38Denmark5275StrokeTroponin+ECG24473
Lee et al39Korea5667StrokeTroponin+ECG124781
Liao et al40Canada5272StrokeTroponin+ECG71991292
Mathias et al41USA5264StrokeTroponin+ECG+echo32372
Prosser et al,42 VISTACanada, Germany, Sweden, UK, USA4973StrokeCardiac mortality & serious cardiac adverse events458337
Song et al43Korea5672StrokeTroponin+ECG35600
  • AMISTAD, Asymptomatic Myocardial Ischemia in Stroke and Atherosclerotic Disease; CAD, coronary artery disease; CCS, coronary calcium score; CTCA, CT coronary angiography; MASS, Multiple Atherosclerosis Site in Stroke; MI, myocardial infarction; TIA, transient ischaemic attack.