exp CYCLOOXYGENASE-2

(cyclo-oxygenase-2^* or COX-2^*). mp.[mp=title, abstract, subject headings, heading word, original title, drug trade name, drug manufacturer]

1 or 2

(gene^* or polymorphism^* or variation^* or genotype^* or genetic^* or mutation^*).mp.[mp=title, abstract, subject headings, heading word, original title, drug trade name, drug manufacturer]

exp liver cell carcinoma/

exp liver tumour/

(((liver or hepatic or hepatocellular or hepato-cellular) and (carcinom* or cancer* or neoplasm* or malign* or tumo*)) or HCC).mp.[mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer]

5 or 6 or 7

3 and 4 and 8