Adjusted negative binomial regression models for polypharmacy and excessive polypharmacy in all individuals
| Polypharmacy* | Excessive polypharmacy† | |||
|---|---|---|---|---|
| Adjusted IRR‡ | 95% CI | Adjusted IRR§ | 95% CI | |
| Year | ||||
| 1997 (reference) | 1 | – | 1 | – |
| 2002 | 2.18 | (1.69 to 2.82) | 3.53 | (2.86 to 4.36) |
| 2007 | 3.49 | (2.71 to 4.49) | 8.07 | (6.55 to 9.93) |
| 2012 | 4.16 | (3.23 to 5.36) | 10.53 | (8.58 to 12.91) |
*Polypharmacy defined as 5 or more regular medicines.
†Excessive polypharmacy defined as 10 or more regular medicines.
‡Adjusted for age group and gender (both significant, p<0.01).
§Adjusted for age group, gender and age group-gender interaction (all significant, p<0.01).
IRR, incident rate ratio.