Table 1

Baseline characteristics of the patients with HCV with or without NAFLD

 AllNAFLD
N=1354Yes
N=433
No
N=921
p Values
Age (years)47.2±16.147.6±15.946.9±16.30.535
Male gender, n (%)580 (42.8%)169 (39.0%)411 (44.6%)0.052
Body weight (kg)65.9±13.366.1±13.365.8±13.30.734
BMI (kg/m2)25.0±4.125.2±4.224.9±4.10.263
BMI >25, n (%)645 (47.6%)211 (48.7%)434 (47.1%)0.581
Waist circumference (cm)82.5±11.382.8±11.182.4±11.40.530
Waist-hip ratio0.9±0.010.9±0.10.9±0.10.960
Systolic BP (mm Hg)136.1±20.6138.1±19.9135.2±20.80.016
Diastolic BP (mm Hg)81.0±14.482.2±13.580.5±14.80.034
Pulse pressure (mm Hg)55.1±13.955.6±13.654.7±14.00.174
Medical and personal history
 Diabetes mellitus, n (%)161 (11.9%)88 (20.3%)73 (7.9%)<0.001
 Hypertension, n (%)287 (21.2%)132 (30.5%)155 (16.8%)<0.001
 Hepatitis B virus, n (%)202 (14.9%)61 (14.1%)141 (15.3%)0.556
 Smoking, n (%)218 (16.1%)59 (13.6%)159 (17.3%)0.089
 Betel chewing, n (%)139 (10.3%)36 (8.3%)103 (11.2%)0.105
Laboratory data
 Creatinine (mg/dL)0.9±0.40.9±0.40.9±0.40.185
 Fasting glucose (mg/dL)*100.2 (92.7, 113)102.8 (95, 119.1)99 (92, 111)<0.001
 Fasting glucose (log value)4.67±0.244.70±0.254.65±0.23<0.001
 ALT (mg/dL)*29 (19, 45)30 (21, 45)29 (19, 45)0.378
 ALT (log value)3.44±0.673.44±0.643.43±0.680.834
 AST (mg/dL)*26 (21, 37)26 (20, 35)27 (21, 38)0.008
 AST (log value)3.38±0.523.33±0.503.41±0.520.017
 ALT/AST ratio1.1±0.41.2±0.41.1±0.4<0.001
 GGT (U/L)*22 (15, 39)25 (17, 38)21 (15, 39)0.008
 GGT (log value)3.27±0.763.30±0.673.26±0.800.300
 Uric acid (mg/dL)6.1±1.66.1±1.66.1±1.60.700
 LDL-C (mg/dL)113.1±31.3115.1±30.5112.2±31.70.110
 HDL-C mg/dL50.9±13.449.1±12.251.8±13.90.001
 Cholesterol mg/dL183.6±36.3186.3±36.6182.4±36.10.064
 Triglyceride (mg/dL)96 (71, 132)109 (79, 146.5)93 (67, 124)<0.001
 Triglyceride (log value)4.60±0.484.72±0.494.54±0.46<0.001
MetS, n (%)398 (29.4%)160 (37.0%)238 (25.8%)<0.001
  • *Data were presented as the median (25th centile, 75th centile) due to the lack of normal distribution and were compared between groups using the Mann-Whitney U test for fasting glucose, ALT, AST, GGT, TG; χ2 test for categorical variables or t test for continuous variables.

  • ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; BP, blood pressure; BW, body weight; GGT, γ-glutamyl transferase; HBV, hepatitis B virus; HCV, hepatitis C virus; HDL-C, high-density lipoprotein-cholesterol; LDL-C, low-density lipoprotein-cholesterol; MetS, metabolic syndrome; NAFLD, non-alcoholic fatty liver disease.