Table 4

AUC of AA and other non-invasive indices in the estimation cohort

Index	All patients		Patients with ALT <2×ULN		Patients with HBeAg negative
Index	AUC (95% CI)	SE	AUC (95% CI)	SE	AUC (95% CI)	SE
AA	0.822 (0.714 to 0.930)*	0.055	0.845 (0.718 to 0.971)*	0.064	0.893 (0.779 to 0.999)*	0.058
AAR	0.554 (0.411 to 0.697)	0.073	0.566 (0.406 to 0.727)	0.082	0.638 (0.447 to 0.829)	0.098
FIB-4	0.691 (0.555 to 0.827)*	0.070	0.643 (0.470 to 0.815)	0.088	0.614 (0.398 to 0.829)	0.110
Forns	0.687 (0.554 to 0.820)*	0.068	0.690 (0.534 to 0.847)*	0.080	0.636 (0.417 to 0.856)	0.112
APRI	0.707 (0.579 to 0.834)*	0.065	0.690 (0.546 to 0.835)*	0.074	0.685 (0.484 to 0.886)	0.103
Fibro Q	0.661 (0.517 to 0.804)*	0.073	0.667 (0.494 to 0.839)*	0.088	0.675 (0.469 to 0.882)	0.105
APGA	0.758 (0.635 to 0.881)*	0.063	0.748 (0.605 to 0.892)*	0.073	0.695 (0.502 to 0.887)	0.098
PAPAS	0.630 (0.491 to 0.769)	0.071	0.621 (0.462 to 0.781)	0.081	0.565 (0.344 to 0.786)	0.113
GUCI	0.729 (0.607 to 0.851)*	0.062	0.719 (0.583 to 0.855)*	0.069	0.714 (0.521 to 0.908)*	0.099
RPR	0.723 (0.589 to 0.858)*	0.069	0.703 (0.531 to 0.875)*	0.088	0.682 (0.466 to 0.897)	0.110
GP	0.671 (0.526 to 0.817)*	0.074	0.710 (0.546 to 0.874)*	0.084	0.685 (0.476 to 0.894)	0.107

*p<0.05.
AAR, aspartate aminotransferase to ALT ratio; APGA, α-fetal protein index; APRI, aspartate aminotransferase to platelet ratio index; ALT, alanine aminotransferase; AUC, area under curve; FIB-4, international normalised ratio index; GP, globulin-platelet model; GUCI, Göteborg University Cirrhosis Index; HBeAg, hepatitis B e antigen; PAPAS, aspartate aminotransferase index; RPR, red cell distribution width to platelet ratio; ULN, upper limit of normal.