Table 1

Input parameters for decision analysis model

Variable (reference)Comment
Life expectancy in years
 Life expectancy of a healthy baby1765
 Life expectancy of an HIV-positive baby with ART1630
 Life expectancy of an HIV-positive baby without ART272
Probabilities
 Probability of HIV incidence rate in pregnant women0.0012 (95% CI 0.00032 to 0.00297)Based on new HIV infections detected during the second HIV test in our study
 Probability of receiving ART in women detected with HIV in the second test0.5 (95% CI 0.33 to 0.964)Based on our study findings
 Probability of breast feeding1Based on our study findings
Cost (US$, US$1= 50 INR)
 Cost of first HIV test14 15US$3.33
 Cost of second HIV test14 15US$3.33
 Cost of ART for PMTCT18US$178.75
 Cost of HIV testing (HIV PCR)US$16.0Based on cost to Prayas's EGPAF's PMTCT programme
 Cost of ART for HIV-infected baby18US$194.0
QALY
 QALY of HIV uninfected baby19 201
 QALY of HIV-infected baby on ART19 200.83
 QALY of HIV-positive baby without ART19 200.73
QALY gained
 QALY gained* for healthy baby (HIV uninfected/HIV-negative baby)1765
 QALY gained for HIV-positive baby on ART2024.9
 QALY gained for HIV-positive baby without ART201.46
  • *QALY gained=QALY×life expectancy.

  • ART, antiretroviral treatment; EGPAF, Elizabeth Glaser Pediatric AIDS Foundation; PMTCT, prevention of mother-to-child transmission; QALY, quality-adjusted life years.