Author | Design | Population | Setting | Intervention of interest | Cointerventions | Primary outcomes | Outcome measurement |
---|---|---|---|---|---|---|---|
Agnew et al18 | Pragmatic, non-randomised, controlled trial | 115 patients (age not specified) presenting with RTI | 4 general practitioners in 1 teaching practice |
| Delayed antibiotic prescriptions for all patients | Antibiotic use | Telephone questionnaire after 10–14 days |
Everitt et al22 | Open, factorial, randomised controlled trial | 307 patients; adults and children (aged 1 year or more) presenting with acute infective conjunctivitis | 38 general practitioners and practice nurses in 30 general practices in England |
|
|
| Validated patient diaries after 14 days |
Francis et al17 | Cluster randomised controlled trial | 558 patients; children (aged 6 months to 14 years) presenting with an acute RTI | General practitioners in 61 general practices in Wales and England |
| General practitioners received online training for the use of the booklet in which the use of certain communication skills was facilitated | Reconsultation rates | Telephone questionnaire with the child's parent or guardian after 14 days |
Gauld et al23 | Randomised controlled trial | 62 patients; female adults (aged 15–64 years) presenting with symptoms of urinary tract infection for whom the doctor prescribed an antibiotic | 18 general practitioners in 8 general practices in England |
| Standard verbally advice at the end of the consultation |
| Interview in the patient's home after 4 or 5 days |
Little et al19 | Factorial randomised controlled trial | 807 patients; adults and children (aged 3 years or more) presenting with acute, uncomplicated lower RTI | 37 physicians in England |
|
|
| Validated patient diaries after 1 month |
Macfarlane et al20 | Single blind randomised controlled trial | 1014 patients; adults (aged 16 years or more) presenting with acute lower RTI | 76 general practitioners |
| – | Reconsultation rates | General practitioners’ records after 1 month |
Macfarlane et al21 | Nested, single blind, randomised controlled trial | 259 patients; adults (aged 16 years or more) presenting with acute lower RTI | General practitioners in 3 general practices in England |
| Delayed prescription for all patients Standard verbal information |
| Patient diaries and telephone interviews after 1 month and 1–2 weeks, respectively |
Sustersic et al24 | Cluster randomised controlled trial | 400 patients; adults and children presenting with gastroenteritis or tonsillitis | 24 general practitioners |
| – | Patient behaviour | Telephone questionnaire with the patient or the adult accompanying the child after 10–15 days |
RTI, respiratory tract infection.