Table 3

Association between age, education, profession, pregnancy status, geographical region and average risk perception scores for the four groups of outcome variables (OTC and prescription medicines, cranberry and ginger, eggs and blue veined cheese, Alcohol and smoking) and thalidomide

			Unadjusted			Adjusted*
Outcome	Predictor	n	Coefficient	95% CI	p Value	Coefficient	95% CI	p Value
OTC and prescription medicines (n=6945)
Age band (years)					<0.001			<0.001
15–20		201	0.20	(−0.05 to 0.44)		0.02	(−0.24 to 0.27)
21–25		1223	0.14	(0.03 to 0.26)		0.07	(−0.05 to 0.19)
26–30		2546	Ref	–		Ref	–
31–35		2012	−0.21	(−0.31 to −0.11)		−0.19	(−0.29 to 0.09)
36–40		817	−0.24	(−0.38 to −0.10)		−0.21	(−0.34 to 0.07)
41–55		146	−0.07	(−0.35 to 0.22)		−0.04	(−0.33 to 0.24)
Education					<0.001			<0.001
Primary		272	0.43	(0.21 to 0.64)		0.36	(0.14 to 0.58)
High-school		1907	0.35	(0.25 to 0.44)		0.30	(0.20 to 0.40)
University		3940	Ref	–		Ref	–
Other		826	0.28	(0.15 to 0.41)		0.26	(0.13 to 0.39)
Health professional		1107	−0.74	(−0.85 to −0.63)	<0.001	−0.71	(−0.82 to −0.60)	<0.001
First pregnancy		3489	0.24	(0.16 to 0.32)	<0.001	0.22	(0.14 to 0.31)	<0.001
Pregnant now		3721	−0.06	(−0.14 to 0.02)	0.159	−0.07	(−0.15 to 0.02)	0.123
Regions					0.004			0.003
Europe
Northern		2129	Ref	–		Ref	–
Western		2630	0.78	(−0.03 to 1.60)		0.81	(−0.01 to 1.62)
Eastern		1596	1.51	(0.67 to 2.36)		1.57	(0.72 to 2.41)
North America		415	0.41	(−0.68 to 1.50)		0.47	(−0.62 to 1.56)
Australia		175	−0.27	(−1.68 to 1.14)		−0.18	(−1.59 to 1.22)
Thalidomide (n=2692)
Age band (years)					<0.001			<0.001
15–20		52	−0.73	(−1.19 to −0.27)		−0.51	(−0.98 to −0.04)
21–25		289	−0.48	(−0.70 to −0.26)		−0.42	(−0.64 to −0.20)
26–30		881	Ref	–		Ref	–
31–35		920	0.20	(0.04 to 0.35)		0.17	(0.02 to 0.32)
36–40		453	0.35	(0.16 to 0.53)		0.31	(0.13 to 0.50)
41–55		97	0.18	(−0.16 to 0.53)		0.18	(−0.17 to 0.52)
Education					<0.001			<0.001
Primary		66	−0.62	(−1.03 to −0.21)		−0.44	(−0.86 to −0.03)
High-school		605	−0.47	(−0.62 to −0.32)		−0.36	(−0.52 to −0.20)
University		1727	Ref	–		Ref	–
Other		294	−0.17	(−0.37 to 0.04)		−0.10	(−0.31 to 0.11)
Health professional		694	0.21	(0.07 to 0.36)	0.004	0.13	(−0.02 to 0.27)	0.091
First pregnancy		1256	−0.05	(−0.18 to 0.07)	0.401	0.03	(−0.10 to 0.16)	0.615
Pregnant now		1382	−0.12	(−0.25 to 0.01)	0.061	−0.08	(−0.21 to 0.05)	0.212
Regions					0.577			0.724
Europe
Northern		708	Ref	–		Ref	–
Western		1259	0.08	(−0.29 to 0.45)		0.07	(−0.30 to 0.43)
Eastern		443	−0.05	(−0.45 to 0.34)		−0.01	(−0.40 to 0.37)
North America		186	−0.30	(−0.80 to 0.20)		−0.27	(−0.77 to 0.22)
Australia		96	0.13	(−0.51 to 0.77)		0.03	(−0.61 to 0.66)
Cranberries and ginger (n=8058)
Age band (years)					0.064			0.065
15–20		258	0.19	(−0.04 to 0.43)		0.17	(−0.07 to 0.42)
21–25		1447	0.05	(−0.06 to 0.17)		0.04	(−0.07 to 0.16)
26–30		2946	Ref	–		Ref	–
31–35		2333	0.05	(−0.05 to 0.15)		0.05	(−0.05 to 0.15)
36–40		912	0.20	(0.06 to 0.34)		0.21	(0.07 to 0.35)
41–55		162	0.18	(−0.11 to 0.48)		0.19	(−0.10 to 0.48)
Education					0.780			0.798
Primary		310	0.03	(−0.19 to 0.24)		0.01	(−0.21 to 0.24)
High-school		2202	0.05	(−0.05 to 0.15)		0.05	(−0.05 to 0.15)
University		4631	Ref	–		Ref	–
Other		915	0.00	(−0.13 to 0.14)		0.00	(−0.13 to 0.14)
Health professional		1124	0.08	(−0.03 to 0.20)	0.165	0.10	(−0.02 to 0.22)	0.102
First pregnancy		4066	0.04	(−0.04 to 0.13)	0.282	0.06	(−0.02 to 0.15)	0.139
Pregnant now		4353	−0.03	(−0.11 to 0.05)	0.510	−0.02	(−0.10 to 0.06)	0.651
Regions					0.450			0.461
Europe
Northern		2584	Ref	–		Ref	–
Western		2719	0.29	(−0.27 to 0.85)		0.27	(−0.28 to 0.83)
Eastern		2076	<0.01	(−0.58 to 0.58)		0.01	(0.57 to 0.58)
North America		473	−0.12	(−0.86 to 0.63)		−0.12	(−0.86 to 0.62)
Australia		206	−0.50	(−1.46 to 0.47)		−0.52	(−1.48 to 0.44)
Egg and blue veined cheese (n=8339)
Age band (years)					<0.001			0.002
15–20		243	−0.09	(−0.39 to 0.22)		−0.15	(−0.46 to 0.17)
21–25		1464	0.09	(−0.06 to 0.23)		0.06	(−0.08 to 0.21)
26–30		3034	Ref	–		Ref	–
31–35		2456	−0.14	(−0.26 to −0.01)		−0.13	(−0.26 to −0.01)
36–40		970	−0.13	(−0.30 to 0.04)		−0.12	(−0.29 to 0.05)
41–55		172	−0.66	(−1.02 to −0.30)		−0.66	(−1.01 to −0.30)
Education					0.033			0.101
Primary		319	0.11	(−0.15 to 0.38)		0.10	(−0.18 to 0.37)
High-school		2318	0.13	(0.01 to 0.25)		0.10	(−0.02 to 0.22)
University		4751	Ref	–		Ref	–
Other		951	0.20	(0.04 to 0.37)		0.19	(0.02 to 0.36)
Health professional		1169	−0.06	(−0.20 to 0.09)	0.452	−0.05	(−0.19 to 0.10)	0.545
First pregnancy		4219	0.29	(0.19 to 0.39)	<0.001	0.28	(0.17 to 0.39)	<0.001
Pregnant now		4497	0.14	(0.04 to 0.25)	0.006	0.13	(0.03 to 0.24)	0.011
Regions					0.010			0.008
Europe
Northern		2654	Ref			Ref
Western		2993	0.81	(0.06 to 1.56)		0.83	(0.09 to 1.58)
Eastern		2035	−0.22	(−1.00 to 0.55)		−0.20	(−0.97 to 0.57)
North America		446	−0.47	(−1.47 to 0.53)		−0.44	(−1.44 to 0.55)
Australia		211	0.88	(−0.41 to 2.18)		0.94	(−0.35 to 2.22)
Alcohol and smoking (n=8701)
Age band (years)					0.003			0.005
15–20		278	−0.27	(−0.48 to −0.06)		−0.25	(−0.47 to −0.03)
21–25		1583	−0.08	(−0.19 to 0.02)		−0.08	(−0.19 to 0.03)
26–30		3161	Ref	–		Ref	–
31–35		2509	−0.14	(−0.23 to −0.04)		−0.14	(−0.23 to −0.05)
36–40		988	−0.11	(−0.24 to 0.01)		−0.12	(−0.24 to 0.01)
41–55		182	−0.37	(−0.63 to −0.11)		−0.37	(−0.63 to −0.11)
Education					0.542			0.694
Primary		358	0.13	(−0.32 to 0.06)		0.10	(−0.30 to 0.09)
High-school		2432	0.01	(−0.09 to 0.08)		0.00	(−0.09 to 0.09)
University		4912	Ref	–		Ref	–
Other		999	0.03	(−0.10 to 0.15)		0.03	(−0.09 to 0.15)
Health professional		1188	0.10	(−0.01 to 0.21)	0.072	0.09	(−0.02 to 0.20)	0.114
First pregnancy		4382	−0.02	(−0.09 to 0.06)	0.637	−0.03	(−0.11 to 0.04)	0.403
Pregnant now		4702	−0.04	(−0.11 to 0.04)	0.347	−0.04	(−0.12 to 0.03)	0.272
Regions					0.284			0.274
Europe
Northern		2699	Ref	–		Ref	–
Western		3047	−0.11	(−0.48 to 0.26)		−0.10	(−0.46 to 0.27)
Eastern		2261	−0.19	(0.57 to 0.19)		−0.20	(0.58 to 0.18)
North America		485	−0.32	(−0.82 to 0.18)		−0.32	(−0.81 to 0.18)
Australia		212	−0.68	(−1.33 to −0.03)		−0.67	(−1.31 to −0.02)

Significant findings are marked in bold.
*Adjusted analyses were all adjusted for age and education.