Table 2

Regression models, derived in this study, for hypertension onset age

To examineData setRegression model
Interaction term between diabetes status and BMIPooled data—both the data sets are pooled together (N=5307)Ŷ=60.49−0.36 (× BMI)−2.94 (× sex=male)−0.12 (BMI×diabetes status=yes)+12.73 (× diabetes status=yes)
p Value for the term (BMI×diabetes status=yes)=0.02
Interaction term between sex and BMIPooled data—both the data sets are pooled together (N=5307)Ŷ=65.70−0.33 (× BMI)−9.0 (× sex=male)−0.37 (BMI×sex=male)
p Value for the term (BMI×sex=male) <0.001
Association of BMI with age at onset of hypertension in patients with diabetesData set of hypertension in patients with diabetes (N=3904)Ŷ=70.13−[(0.39×(BMI)]−[(0.27×sex=male)×(BMI)]+[5.6×(sex=male)]
Translates onto
Onset age (in men)=75.73−0.66×(BMI):
Onset age (in women)=70.13−0.39×(BMI)
Slope of onset age on BMI (men)=−0.66
Slope of onset age on BMI (women)=−0.39
Association of BMI with age at onset of hypertension in patients without diabetesData set of hypertension in patients without diabetes (N=1403)Ŷ=54.34−[0.18×(BMI)]−[(0.44×sex=male)×(BMI)]+[11.72×(sex=male)]
Translates onto
Onset age (in men)=66.06−0.62×(BMI):
Onset age (in women)=54.34−0.18×(BMI):
Slope of onset age on BMI (men)=−0.62
Slope of onset age on BMI (women)=−0.18
Confounding due to antidiabetic medicationData set of hypertension in patients with diabetes(N=3904)Ŷ=70.28−[0.39×(BMI)]−[(0.27×sex=male)×(BMI)]+[5.6×(Sex=male)]−[0.39 (× medication status=yes)]
p Value for the term (medication status=yes)=0.4
Association of BMI with age at onset of hypertension in participants destined to develop diabetesData set of diabetes onset after that of hypertension
(N=575)
Ŷ=61.64−[−0.32× (BMI)]−[(0.36×Sex=male)×(BMI)]+[9.13×(sex=male)].
  • BMI, body mass index.