Table 3

Comparison of the proportion of patients with low BMD, abnormal blood lipid and blood glucose levels, overweight and obesity between GC users and non-GC users

RR value (GC users vs non-GC users)Non-GC usersGC usersGrouping by duration of GC therapy
GCs<0.5 yearsGCs 0.5–2 yearsGCs >2 years
BMD
 Number of cases111206268991
 Low BMD, n (%)1.15 (0.74–1.78)23 (20.7)49 (23.8)4 (15.4)24 (27.0)21 (23.1)
Blood lipids
 Number of cases61129226839
 Elevated CHOL, n (%)2.84 (0.66–12.35)2 (3.3)12 (9.3)2 (9.1)9 (13.2)1 (2.6)
 Elevated TG, n (%)0.68 (0.31–1.51)9 (14.8)13 (10.1)2 (9.1)8 (11.8)3 (7.7)
 Decreased HDL,* n (%)0.64 (0.11–3.75)2 (3.6)3 (2.3)02 (3.0)1 (2.6)
 Elevated LDL,* n (%)2.18 (0.26–18.18)1 (2.5)4 (4.1)1 (4.5)3 (4.6)1 (2.6)
Blood glucose
 Number of cases136199549252
 Elevated glucose, n (%)0.273 (0.05–1.39)5 (3.7)2 (1.0)02 (2.2)0
BMI
 Number of cases1372303111980
 Overweight, n (%)0.74 (0.49–1.11)33 (24.1)41 (17.8)5 (16.1)20 (16.8)16 (20.0)
 Obesity, n (%)1.64 (0.53–5.05)4 (2.9)11 (4.8)08 (6.7)3 (3.8)
  • All the p values between the GC subgroup (GCs <0.5, 0.5–2 or >2 years) and non-GC users were over 0.05.

  • *Out of the patients who had their blood lipids tested after treatment, six cases missed the data of HDL, and eight cases missed the data of LDL.

  • BMD, bone mineral density; BMI, body mass index; CHOL, cholesterol; GC, glucocorticoid; HDL, high-density lipoprotein; LDL, low-density lipoprotein; RR, relative risk; TG, triglyceride.