Table 2

Demographic characteristics and medical history of cases (switchers) and controls (non-switchers) at the time of the switch and identification of factors associated with switching to Respimat

CharacteristicsCases (switchers)Controls (non-switchers)Crude OR95% CIAdjusted OR95% CI
Number of participants359359
Mean age, years (SD)73 (10)76 (10)
N%N%
Age class (years)
 45–646718.74813.4refref
 65–7412334.39727.00.910.58 to 1.430.880.55 to 1.42
 ≥7516947.121459.60.570.37 to 0.860.520.33 to 0.81
Gender
 Male22462.022663.01.020.76 to 1.391.070.77 to 1.47
 Female13538.013337.0refref
Severity of respiratory disease
 No respiratory drugs4412.37520.9refref
 1 class of respiratory drugs11532.014540.41.350.87 to 2.111.310.82 to 2.06
 2 classes of respiratory drugs7821.77721.41.731.06 to 2.811.630.98 to 2.72
 3 classes of respiratory drugs4713.13710.32.171.23 to 3.831.961.06 to 3.61
 ≥4 classes of respiratory drugs7520.9257.05.112.85 to 9.194.622.46 to 8.69
Previous drug use (tracer of comorbidity)
 Antiarrhythmics277.5215.81.310.73 to 2.261.530.82 to 2.85
 β-Blockers6217.34813.41.350.90 to 2.041.761.13 to 2.75
 Other cardiovascular drugs7220.06518.10.880.61 to 1.280.920.61 to 1.39
 Antibiotics25871.921158.81.791.31 to 2.451.340.94 to 1.89
 Lipid-lowering agents8122.610429.00.710.51 to 1.000.680.47 to 0.97
 Pain medications (opioids)267.24011.10.620.37 to 1.040.610.35 to 1.05
 Antiglaucoma agents349.5215.81.680.96 to 2.961.630.90 to 2.95
 Antiplatelet/anticoagulant agents18451.318351.01.010.75 to 1.351.280.90 to 1.80
 Antidiabetics5816.26217.30.920.62 to 1.370.890.58 to 1.36
 Antipsychotics113.1102.81.100.46 to 2.631.330.53 to 3.34
 Antiparkinsons123.392.51.340.56 to 3.231.600.63 to 4.08
 Antidepressives6016.77119.80.810.56 to 1.190.800.53 to 1.20
 Antiepileptics205.6267.20.760.41 to 1.380.800.42 to 1.54
 Antacids19554.318852.41.080.81 to 1.451.000.72 to 1.40
 NSAIDs8924.87220.11.310.92 to 1.871.200.82 to 1.76
 Osteoporosis medications298.1298.11.000.59 to 1.710.960.55 to 1.68
  • NSAIDs, non-steroidal anti-inflammatory drugs.