Table 1

Demographic characteristics and medical history of incident users of Handihaler or Respimat formulation and of factors associated with Respimat prescription

CharacteristicsHandihalerRespimatCrude OR95% CIAdjusted OR95% CI
Number of participants3492898
Mean age, years (SD)74 (10)73 (10)
NPer centNPer cent
Age class (years)
 45–6464118.420522.8refref
 65–74101929.226729.70.820.67 to 1.010.800.65 to 0.99
 ≥75183252.542647.40.730.60 to 0.880.700.58 to 0.85
Gender
 Male197656.651257.01.020.88 to 1.181.030.89 to 1.20
 Female151643.438643.0refref
Severity of respiratory disease
 No respiratory drugs132237.931635.2refref
 1 class of respiratory drugs91826.321924.41.000.82 to 1.210.970.80 to 1.18
 2 classes of respiratory drugs56716.215517.31.140.92 to 1.421.110.89 to 1.38
 3 classes of respiratory drugs35710.29510.61.110.86 to 1.441.080.82 to 1.40
 ≥4 classes of respiratory drugs3289.411312.61.441.13 to 1.841.411.09 to 1.83
Previous drug use (tracer of comorbidity)
 Antiarrhythmics2256.4606.71.040.77 to 1.401.050.78 to 1.42
 β-Blockers79122.723826.51.231.04 to 1.461.291.08 to 1.52
 Other cardiovascular drugs262375.166874.40.960.81 to 1.141.000.83 to 1.20
 Antibiotics216562.060667.51.271.09 to 1.481.231.04 to 1.45
 Lipid-lowering agents96427.625428.31.030.88 to 1.221.060.89 to 1.26
 Pain medications (opioids)3068.8798.81.000.78 to 1.300.990.76 to 1.28
 Antiglaucoma agents1885.4566.21.170.86 to 1.591.250.92 to 1.71
 Antiplatelet/anticoagulant agents172949.544950.01.020.88 to 1.181.080.92 to 1.27
 Antidiabetics64418.713715.30.800.65 to 0.970.760.62 to 0.94
 Antipsychotics872.5313.51.400.92 to 2.121.320.87 to 2.02
 Antiparkinsons842.4323.61.500.99 to 2.691.651.08 to 2.51
 Antidepressives67219.215817.60.900.74 to 1.090.860.71 to 1.05
 Antiepileptics1995.7626.91.230.91 to 1.651.190.88 to 1.60
 Antacids186253.346351.60.930.81 to 1.080.890.77 to 1.04
 NSAIDs90025.822525.10.960.81 to 1.140.930.78 to 1.10
 Osteoporosis medications2607.4637.00.940.71 to 1.250.920.69 to 1.23
  • NSAIDs, non-steroidal anti-inflammatory drugs.