Table 4

Crude and adjusted associations between stage of disease at breast cancer diagnosis and mortality during the first year following a diagnosis of bone metastasis in patients with breast cancer (N=2427)

Crude HR (95% CI)Adjusted HR* (95% CI)
Stage of disease at breast cancer diagnosis
 LocalisedReferenceReference
 Regional1.29 (1.08 to 1.52)1.34 (1.13 to 1.60)
 Metastatic1.23 (1.02 to 1.49)2.12 (1.71 to 2.62)
 Unknown1.33 (1.03 to 1.70)1.55 (1.20 to 2.00)
  • *Adjusted for age at breast cancer diagnosis, time period of breast cancer diagnosis, estrogen receptor status, level of comorbidity, other metastases recorded at or before bone metastasis diagnosis and length of bone metastasis-free interval.