Mortality according to diagnosed diabetes
| Men | DM(−) (n=43 256) | DM(+) (n=2761) | HR | Excluding cases during first 5 years | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Rate* | Cases | Rate* | Crude | Multivariate-adjusted* | Multivariate-adjusted* HR | ||||
| All-cause | 7367 | 98.0 | 856 | 163.9 | 1.65 | (1.54–1.77) | 1.60 | (1.49–1.71) | 1.59 | (1.47–1.71) |
| All circulatory system diseases (ICD-10:I00-I99) | 1744 | 23.2 | 230 | 43.6 | 1.88 | (1.63–2.15) | 1.76 | (1.53–2.02) | 1.79 | (1.54–2.09) |
| Ischaemic heart disease (ICD-10:I20-I25) | 434 | 5.8 | 76 | 14.2 | 2.47 | (1.93–3.15) | 2.30 | (1.80–2.95) | 2.32 | (1.78–3.03) |
| Cerebrovascular disease (ICD-10:I60-I69) | 705 | 9.4 | 88 | 16.7 | 1.78 | (1.43–2.23) | 1.68 | (1.34–2.10) | 1.75 | (1.37–2.23) |
| Cerebral infarction (ICD-10:I63) | 176 | 2.3 | 27 | 4.9 | 2.07 | (1.38–3.11) | 1.87 | (1.24–2.82) | 1.76 | (1.09–2.82) |
| Intracerebral haemorrhage (ICD-10:I61) | 227 | 3.0 | 27 | 5.6 | 1.86 | (1.25–2.78) | 1.73 | (1.16–2.59) | 2.00 | (1.30–3.07) |
| All-cancer (ICD-10:C00-C97) | 3093 | 41.2 | 283 | 53.6 | 1.28 | (1.13–1.45) | 1.25 | (1.11–1.42) | 1.22 | (1.06–1.39) |
| All sites excluding the liver | 2850 | 37.9 | 244 | 46.0 | 1.20 | (1.05–1.37) | 1.18 | (1.03–1.34) | 1.16 | (1.00–1.34) |
| All sites excluding the liver and pancreas | 2652 | 35.3 | 216 | 40.5 | 1.14 | (0.99–1.31) | 1.12 | (0.97–1.29) | 1.11 | (0.95–1.29) |
| Oesophagus (ICD-10:C15) | 171 | 2.3 | 16 | 3.0 | 1.35 | (0.80–2.25) | 1.31 | (0.78–2.20) | 1.01 | (0.53–1.93) |
| Stomach (ICD-10:C16) | 543 | 7.2 | 37 | 7.2 | 0.95 | (0.68–1.32) | 0.92 | (0.66–1.29) | 0.73 | (0.49–1.11) |
| Colon (ICD-10:C18) | 172 | 2.3 | 19 | 3.6 | 1.62 | (1.01–2.61) | 1.61 | (1.00–2.60) | 1.73 | (1.04–2.87) |
| Rectum (ICD-10:C19-C21) | 146 | 1.9 | 12 | 2.3 | 1.20 | (0.66–2.16) | 1.17 | (0.65–2.12) | 1.29 | (0.67–2.47) |
| Liver (ICD-10:C22) | 243 | 3.2 | 39 | 7.6 | 2.20 | (1.57–3.10) | 2.12 | (1.50–2.98) | 1.89 | (1.27–2.80) |
| Bile duct (ICD-10:C23-C24) | 133 | 1.8 | 17 | 3.1 | 1.78 | (1.07–2.96) | 1.76 | (1.06–2.92) | 1.68 | (0.96–2.94) |
| Pancreas (ICD-10:C25) | 198 | 2.6 | 28 | 5.4 | 1.98 | (1.33–2.95) | 1.95 | (1.31–2.91) | 1.80 | (1.15–2.81) |
| Lung (ICD-10:C33-C34) | 778 | 10.4 | 49 | 9.1 | 0.85 | (0.64–1.14) | 0.84 | (0.63–1.13) | 0.87 | (0.64–1.19) |
| Kidney (ICD-10:C64-C66, C68) | 51 | 0.7 | 10 | 2.1 | 2.75 | (1.39–5.43) | 2.50 | (1.26–4.98) | 2.32 | (1.09–4.98) |
| Bladder (ICD-10:C67) | 39 | 0.5 | 10 | 1.8 | 3.38 | (1.68–6.81) | 3.29 | (1.63–6.65) | 3.63 | (1.78–7.39) |
| Prostate (ICD-10:C61) | 107 | 1.4 | 10 | 1.7 | 1.29 | (0.67–2.47) | 1.24 | (0.65–2.39) | 1.31 | (0.68–2.53) |
| Non-cancer, non-circulatory system disease | 2530 | 33.6 | 343 | 66.7 | 1.96 | (1.75–2.19) | 1.91 | (1.71–2.14) | 1.90 | (1.67–2.15) |
| Women | (n=52 042) | (n=1525) | ||||||||
| All-cause | 4295 | 45.9 | 345 | 102.3 | 2.11 | (1.89–2.35) | 1.98 | (1.77–2.21) | 2.02 | (1.79–2.28) |
| All circulatory system diseases (ICD-10:I00-I99) | 1084 | 11.6 | 123 | 36.6 | 2.82 | (2.33–3.40) | 2.49 | (2.06–3.01) | 2.56 | (2.09–3.13) |
| Ischaemic heart disease (ICD-10:I20-I25) | 196 | 2.1 | 42 | 13.4 | 5.10 | (3.64–7.13) | 4.52 | (3.21–6.37) | 4.56 | (3.17–6.57) |
| Cerebrovascular disease (ICD-10:I60-I69) | 479 | 5.1 | 38 | 11.3 | 2.08 | (1.49–2.90) | 1.72 | (1.23–2.40) | 1.72 | (1.19–2.47) |
| Cerebral infarction (ICD-10:I63) | 98 | 1.1 | 18 | 5.5 | 4.31 | (2.60–7.15) | 3.43 | (2.05–5.74) | 3.61 | (2.12–6.15) |
| Intracerebral haemorrhage (ICD-10:I61) | 136 | 1.5 | 9 | 3.2 | 1.93 | (0.98–3.81) | 1.64 | (0.83–3.24) | 1.71 | (0.83–3.54) |
| All-cancer (ICD-10:C00-C97) | 1841 | 19.6 | 71 | 22.6 | 1.08 | (0.85–1.37) | 1.04 | (0.82–1.32) | 1.05 | (0.81–1.36) |
| All sites excluding the liver | 1730 | 18.4 | 61 | 19.9 | 1.00 | (0.77–1.29) | 0.96 | (0.74–1.24) | 0.93 | (0.70–1.24) |
| All sites excluding the liver and pancreas | 1540 | 16.4 | 52 | 17.3 | 0.97 | (0.73–1.27) | 0.93 | (0.71–1.23) | 0.90 | (0.66–1.23) |
| Stomach (ICD-10:C16) | 224 | 2.4 | 8 | 3.4 | 1.05 | (0.52–2.13) | 1.10 | (0.54–2.24) | 1.21 | (0.57–2.60) |
| Colon (ICD-10:C18) | 160 | 1.7 | 5 | 1.7 | 0.84 | (0.35–2.06) | 0.81 | (0.33–2.00) | 0.79 | (0.29–2.15) |
| Liver (ICD-10:C22) | 111 | 1.2 | 10 | 2.6 | 2.30 | (1.20–4.40) | 2.21 | (1.15–4.27) | 2.66 | (1.37–5.17) |
| Pancreas (ICD-10:C25) | 190 | 2 | 9 | 2.6 | 1.22 | (0.62–2.39) | 1.10 | (0.56–2.16) | 1.17 | (0.57–2.39) |
| Lung (ICD-10:C33-C34) | 228 | 2.4 | 8 | 2.1 | 1.00 | (0.49–2.02) | 0.95 | (0.47–2.40) | 0.95 | (0.35–2.61) |
| Non-cancer, non-circulatory system disease | 1370 | 14.7 | 151 | 43.2 | 2.79 | (2.35–3.30) | 2.67 | (2.25–3.17) | 2.66 | (2.22–3.19) |
Rate*: per 10 000 person-years (age-standardised).
Multivariate-adjusted*: adjusted for age, BMI (<18, 18–20.9, 21–22.9, 23–24.9, 25–26.9, ≥27), alcohol intake (non-drinker, <150, 150–299, 300–450, ≥450 g/week (women, ≥300 g/week)), smoking (never, past, <20, ≥20 cigarettes /day), history of hypertension, leisure-time physical activity. Stratified by area.
BMI, body mass index.