Table 3

Comparison of patients using β-blockers versus patients using other BPLMs only from the CPRD and DIN studies: pooled HRs (95% CI) from meta-analyses of cancer site-specific results

Comparison (vs controls)CPRDDINp Value†
All patients using β-blockers1.01 (0.91 to 1.13)1.18 (1.04 to 1.33)**0.06
Patients using β-blockers only0.94 (0.82 to 1.07)1.37 (1.16 to 1.61)***<0.001***
β-Blockers and other BPLM1.06 (0.95 to 1.19)1.11 (0.91 to 1.34)0.69
Non-selective β-blockers only0.96 (0.8 to 1.15)1.21 (0.94 to 1.55)0.14
  • **p<0.01; ***p<0.001.

  • †Wald tests of CPRD vs DIN HRs.

  • BPLMs, blood pressure lowering medicines; CPRD, Clinical Practice Research Datalink; DIN, Doctors’ Independent Network.