Demographics, physiological and clinical parameters at study entry in 478 patients with moderate/severe ARDS
| Variable | Values |
|---|---|
| Age, years, median (IQR) | 55 (40–70) |
| APACHE II score | 21±7 |
| Lung injury score | 2.9±0.7 |
| Tidal volume, mL/kg PBW | 7.2±1.2 |
| PEEP, cm H2O | 9±3 |
| Plateau pressure, cm H2O | 26.5±6 |
| FiO2 | 0.75±0.2 |
| PaO2/FiO2, mm Hg | 118±39 |
| PaCO2, mm Hg | 45±11 |
| Causes of ARDS, n (%) | |
| Pneumonia | 176 (36.8) |
| Sepsis | 144 (30.1) |
| Trauma | 80 (16.7) |
| Aspiration pneumonia | 60 (12.5) |
| Others | 18 (3.8) |
| Number of organ failures | 1.3±1.1 |
| Hospital mortality, n (%) | 202 (42.2) |
ARDS, acute respiratory distress syndrome; PBW, predicted body weight; PaO2/FiO2; ratio of arterial partial pressure of oxygen to fraction of inspired oxygen; PEEP, positive end-expiratory pressure.