Rules for setting PEEP and FiO2 during assessment on standardised settings at 24 h of ARDS diagnosis
| PEEP level before changing to standardised settings | PEEP setting for assessment |
|---|---|
| ≤10 cm H2O | 10 cm H2O |
| >10 and <13 cm H2O | Set at 10 cm H2O, unless SpO2<88%. Then returned to previous level |
| ≥13 cm H2O | Maintain current level and assess |
| FiO2 level before changing to standardised settings | FiO2 setting for assessment |
| ≤0.5 | 0.5 |
| >0.5 and ≤0.6 | Set at 0.5, unless SpO2<88%. Then, returned to previous level |
| >0.6 | Maintain current level and assess |
ARDS, acute respiratory distress syndrome; PEEP, positive end-expiratory pressure.