Most common combinations of conditions and medications in patients with fibromyalgia
| Condition 1 | Condition 2 | N (%) |
|---|---|---|
| Chronic joint pain/degenerative arthritis | Depression | 749 (67.4) |
| Chronic joint pain/degenerative arthritis | Chronic headaches/migraines | 628 (56.5) |
| Chronic joint pain/degenerative arthritis | Anxiety | 569 (51.2) |
| Depression | Anxiety | 560 (50.4) |
| Depression | Chronic headaches/migraines | 553 (49.8) |
| Chronic joint pain/degenerative arthritis | Insomnia | 524 (47.2) |
| Chronic joint pain/degenerative arthritis | Obesity (BMI >30) | 467 (43.2) |
| Chronic joint pain/degenerative arthritis | Hypertension | 473 (43.0) |
| Medication 1 | Medication 2 | |
| Sleep aids | SSRI | 130 (11.7) |
| Sleep aids | Opioids | 103 (9.3) |
| Sleep aids | Other psychiatric medications* | 101 (9.1) |
| Sleep aids | SNRI | 97 (8.7) |
| Sleep aids | α-2-δ ligands | 92 (8.3) |
| Opioids | SSRI | 88 (7.9) |
| Sleep aids | Tramadol | 85 (7.7) |
| Sleep aids | Benzodiazepines | 80 (7.2) |
*Other psychiatric medications include lithium, monoamine oxidase inhibitors, antipsychotics, bupropion, lamotrigine and tetracyclic antidepressants.
BMI, body mass index; SNRI, serotonin norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor.