Change from post-PR values after 12 months, ITT and PP analysis with no imputation
| Control (n=75) | Intervention (n=73) | Mean difference | Intervention (n=38) | Mean difference | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N | Mean | N | Mean | 95% CI | p Value | N | Mean | 95% CI | p Value | |
| CRQ dyspnoea | 57 | −0.54 (1.21) | 53 | −0.35 (1.17) | 0.19 (−0.26 to 0.64) | 0.397 | 34 | −0.37 (1.30) | 0.17 (−0.36 to 0.71) | 0.522 |
| CRQ fatigue | 58 | −0.41 (1.19) | 53 | −0.30 (1.09) | 0.12 (−0.31 to 0.55) | 0.592 | 34 | −0.12 (1.06) | 0.3 (−0.19 to 0.79) | 0.233 |
| CRQ emotion | 58 | 0.02 (1.32) | 53 | 0.00 (1.46) | −0.02 (−0.55 to 0.5) | 0.927 | 34 | 0.31 (1.59) | 0.29 (−0.32 to 0.9) | 0.353 |
| CRQ mastery | 58 | −0.06 (1.49) | 53 | 0.01 (1.42) | 0.07 (−0.48 to 0.62) | 0.8 | 34 | 0.35 (1.51) | 0.41 (−0.23 to 1.05) | 0.205 |
| ESWT (m) | 40 | −179.29 (451.37) | 40 | −70.22 (487.59) | 109.08 (−100.08 to 318.23) | 0.302 | 28 | 6.91 (477.15) | 186.2 (−41.13 to 413.53) | 0.107 |
| ESWT (s) | 43 | −142.84 (398.91) | 40 | −152.90 (430.32) | −10.06 (−191.16 to 171.03) | 0.912 | 27 | −103.15 (408.95) | 39.69 (−157.66 to 237.04) | 0.689 |
| Body mass index (kg/m2) | 40 | −0.33 (1.52) | 33 | −0.58 (2.71) | −0.25 (−1.26 to 0.75) | 0.617 | 23 | −0.85 (2.85) | −0.52 (−1.62 to 0.58) | 0.345 |
| Body fat (%) | 46 | −0.52 (3.64) | 41 | −0.60 (3.54) | −0.08 (−1.62 to 1.45) | 0.916 | 29 | −0.39 (3.16) | 0.12 (−1.52 to 1.76) | 0.882 |
| HADS | 44 | 0.89 (5.16) | 41 | 0.68 (5.04) | −0.2 (−2.41 to 2) | 0.855 | 28 | 0.11 (5.62) | −0.78 (−3.36 to 1.8) | 0.548 |
| EQ5D | 59 | −0.10 (0.28) | 55 | −0.08 (0.25) | 0.01 (−0.08 to 0.11) | 0.786 | 33 | −0.04 (0.22) | 0.06 (−0.05 to 0.17) | 0.277 |
| Activity (MET-minutes) | 17 | −88.82 (407.53) | 16 | 134.38 (518.16) | 223.2 (−106.68 to 553.08) | 0.177 | 10 | 307.50 (522.97) | 396.32 (24.92 to 767.72) | 0.037 |
| Activity (VAS) | 18 | −4.83 (14.25) | 17 | 11.35 (18.92) | 16.19 (4.71 to 27.66) | 0.007 | 10 | 12.11 (17.40) | 16.94 (4.06 to 29.83) | 0.012 |
| Exacerbation (event per year)* | 75 | 0.57 (1.05) | 73 | 0.56 (1.11) | 0.99 (0.73 to 1.33) | 0.931 | 38 | 0.84 (1.35) | 1.46 (1.06 to 2.01) | 0.021 |
| Hospitalisation (events per year)* | 75 | 0.28 (0.69) | 73 | 0.22 (0.53) | 0.77 (0.51 to 1.16) | 0.204 | 38 | 0.24 (0.59) | 0.82 (0.49 to 1.37) | 0.445 |
*These are the actual values rather than changes.
CRQ, Chronic Respiratory Questionnaire; EQ5D, EuroQol; ESWT, endurance shuttle walk test; HADS, hospital anxiety and depression score; MET, metabolic equivalents; R, pulmonary rehabilitation; VAS, visual analogue scale.