Table 3

Appraisal of risk of bias of the included studies using the Cochrane risk-of-bias tool12

Study1234567
Fonseca et al25UnclearLowLowLowHighLowHigh
Gilman*26UnclearUnclearLowLowHighUnclearHigh
Abdulwahid*27UnclearUnclearLowLowUnclearUnclearUnclear
Lukashevich*28UnclearUnclearLowLowLowLowUnclear
Makdissi et al29UnclearUnclearLowLowUnclearLowLow
Moses et al*30UnclearUnclearLowLowHighUnclearUnclear
Nogueira*31UnclearUnclearLowLowLowUnclearUnclear
Violante et al32UnclearUnclearLowLowHighLowHigh
Owens et al33UnclearUnclearLowLowLowLowHigh
Hermansen et al34LowLowLowLowHighUnclearHigh
  • Items:

  • 1. Random sequence generation.

  • 2. Allocation concealment.

  • 3. Blinding of participants and personnel.

  • 4. Blinding of outcome assessment.

  • 5. Incomplete outcome data.

  • 6. Selective reporting.

  • 7. Other bias.

  • *Unpublished data.

  • High, high risk; Low, low risk; Unclear, unclear risk.