Secondary end points
| Pre | Post1 | Post2 | Post3 | ||
|---|---|---|---|---|---|
| Characteristics | N=328 (24.9%) | N=311 (23.6%) | N=384 (29.2%) | N=293 22.3(%) | p Value |
| Length of ICU stay (days) | 9.2±10.7 | 9.1±9.6 | 9.9±12.1 | 11.3±12.2 | <0.01 |
| Mortality (%) | 34 (10.4%) | 34 (10.9%) | 32 (8.3%) | 26 (8.9%) | 0.624 |
| Antibiotic-free days (%) | 30±27 | 32±28 | 46±39 | 44±38 | <0.01 |