Mortality following an AECOPD according to the number of exacerbations in the previous year
| Frequency of severe AECOPD in the 12 months prior to a severe AECOPD | Number of deaths | Person-years | Mortality rate and 95% CI (per 1000 person-years) | HR and 95% CI* |
|---|---|---|---|---|
| 0–30 days | ||||
| 0 | 283 | 301 | 939 (836 to 1055) | (ref.) |
| 1 | 109 | 114 | 954 (790 to 1151) | 1.07 (0.85 to 1.33) |
| 2 | 52 | 46 | 1123 (855 to 1473) | 1.29 (0.96 to 1.75) |
| 3+ | 32 | 36 | 893 (631 to 1262) | 1.09 (0.75 to 1.59) |
| 31 and up to 365 days | ||||
| 0 | 648 | 2974 | 218 (201 to 235) | (ref.) |
| 1 | 196 | 523 | 375 (326 to 431) | 1.75 (1.49 to 2.06) |
| 2 | 51 | 146 | 349 (265 to 459) | 1.67 (1.26 to 2.23) |
| 3+ | 22 | 59 | 371 (245 to 564) | 1.77 (1.15 to 2.72) |
Northern Denmark, 2005–2009. Only severe (hospitalised) AECOPDs included.
*Adjusted for age (as a continuous variable), sex and comorbidities.
AECOPD, acute exacerbation of chronic obstructive pulmonary disease.