Table 3

Final prioritised and ranked uncertainties for the management of Parkinson's disease

Overarching research aspiration: an effective cure for Parkinson's disease
1What treatments are helpful for reducing balance problems and falls in people with Parkinson's?
2What approaches are helpful for reducing stress and anxiety in people with Parkinson's?
3What treatments are helpful for reducing dyskinesias (involuntary movements, which are a side effect of some medications) in people with Parkinson's?
4Is it possible to identify different types of Parkinson's, eg, tremor dominant? And can we develop treatments to address these different types?
5What best treats dementia in people with Parkinson's?
6What best treats mild cognitive problems such as memory loss, lack of concentration, indecision and slowed thinking in people with Parkinson's?
7What is the best method of monitoring a person with Parkinson's response to treatments?
8What is helpful for improving the quality of sleep in people with Parkinson's?
9What helps improve the dexterity (fine motor skills or coordination of small muscle movements) of people with Parkinson's so they can do up buttons, use computers, phones, remote controls etc?
10What treatments are helpful in reducing urinary problems (urgency, irritable bladder, incontinence) in people with Parkinson's?