Rates of antipsychotic prescribing for the three most commonly prescribed first-generation antipsychotics
Characteristic | Haloperidol | Chlorpromazine | Trifluoperazine | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | Rate per 100 000 PYAR | 95% CI | IRR* | 95% CI | |
Male | 42 | (41 to 44) | 1.000 | 51 | (50 to 53) | 1.000 | 22 | (21 to 23) | 1.000 | |||
Female | 55 | (54 to 57) | 1.123 | (1.107 to 1.138) | 52 | (50 to 53) | 1.121 | (1.107 to 1.135) | 36 | (35 to 38) | 1.577 | (1.547 to 1.607) |
Under 18 | 1 | (1 to 2) | 0.017 | (0.015 to 0.019) | 0.6 | (0.4 to 0.9) | 0.004 | (0.003 to 0.004) | 0.6 | (0.4 to 0.9) | 0.006 | (0.005 to 0.008) |
18–29 | 16 | (15 to 18) | 0.204 | (0.196 to 0.213) | 33 | (31 to 35) | 0.231 | (0.225 to 0.237) | 13 | (12 to 15) | 0.195 | (0.186 to 0.205) |
30–39 | 35 | (33 to 38) | 0.659 | (0.641 to 0.678) | 72 | (68 to 75) | 0.640 | (0.628 to 0.653) | 30 | (28 to 32) | 0.634 | (0.613 to 0.655) |
40–49 | 42 | (40 to 44) | 1.000 | 85 | (82 to 89) | 1.000 | 37 | (35 to 40) | 1.000 | |||
50–59 | 44 | (42 to 47) | 1.085 | (1.058 to 1.112) | 77 | (74 to 81) | 0.992 | (0.974 to 1.010) | 38 | (35 to 40) | 1.046 | (1.015 to 1.078) |
60–69 | 51 | (48 to 54) | 1.175 | (1.145 to 1.205) | 63 | (60 to 67) | 0.822 | (0.806 to 0.839) | 46 | (43 to 49) | 1.378 | (1.339 to 1.419) |
70–79 | 98 | (93 to 104) | 2.123 | (2.073 to 2.175) | 54 | (50 to 58) | 0.613 | (0.598 to 0.629) | 54 | (50 to 58) | 1.739 | (1.687 to 1.792) |
80+ | 330 | (319 to 342) | 5.833 | (5.710 to 5.958) | 58 | (53 to 63) | 0.595 | (0.578 to 0.614) | 72 | (67 to 78) | 1.868 | (1.808 to 1.931) |
Townsend | ||||||||||||
Least deprived | 32 | (30 to 33) | 1.000 | 24 | (22 to 25) | 1.000 | 19 | (18 to 21) | 1.000 | |||
2 | 48 | (46 to 50) | 1.499 | (1.464 to 1.534) | 33 | (32 to 35) | 1.225 | (1.194 to 1.257) | 22 | (20 to 23) | 1.185 | (1.146 to 1.225) |
3 | 53 | (51 to 56) | 1.914 | (1.871 to 1.957) | 46 | (44 to 48) | 2.117 | (2.068 to 2.167) | 28 | (27 to 30) | 1.809 | (1.754 to 1.867) |
4 | 60 | (58 to 63) | 2.360 | (2.307 to 2.413) | 68 | (65 to 71) | 3.131 | (3.062 to 3.202) | 39 | (37 to 41) | 2.839 | (2.756 to 2.925) |
Most deprived | 62 | (58 to 65) | 2.666 | (2.603 to 2.731) | 116 | (112 to 120) | 5.743 | (5.619 to 5.870) | 50 | (47 to 53) | 3.703 | (3.591 to 3.818) |
Missing | 49 | (43 to 56) | 2.315 | (2.217 to 2.417) | 95 | (86 to 103) | 4.103 | (3.961 to 4.250) | 30 | (26 to 35) | 2.113 | (1.987 to 2.246) |
Year | ||||||||||||
2007 | 51 | (49 to 54) | 1.000 | 58 | (55 to 60) | 1.000 | 33 | (31 to 35) | 1.000 | |||
2008 | 54 | (52 to 56) | 1.019 | (0.998 to 1.039) | 56 | (54 to 59) | 0.973 | (0.955 to 0.992) | 31 | (29 to 32) | 0.941 | (0.916 to 0.967) |
2009 | 52 | (50 to 54) | 0.955 | (0.936 to 0.974) | 53 | (51 to 56) | 0.899 | (0.882 to 0.916) | 29 | (27 to 31) | 0.899 | (0.874 to 0.924) |
2010 | 48 | (46 to 50) | 0.822 | (0.805 to 0.840) | 47 | (45 to 49) | 0.824 | (0.807 to 0.840) | 30 | (28 to 32) | 0.901 | (0.876 to 0.926) |
2011 | 39 | (37 to 41) | 0.684 | (0.669 to 0.700) | 44 | (41 to 46) | 0.751 | (0.736 to 0.766) | 24 | (22 to 26) | 0.665 | (0.645 to 0.685) |
*All IRR are adjusted for the other characteristics in this table.
IRR, incident rate ratio; PYAR, person years at risk.