HR (95% CI) of all-cause and cause-specific mortality associated with body mass index category
| 18.5–24.9 kg/m2 | 25–29.9 kg/m2 | 30–34.9 kg/m2 | ≥35 kg/m2 | |
|---|---|---|---|---|
| All-cause mortality | ||||
| Number of deaths | 151 | 267 | 151 | 99 |
| Mortality rate (SE)* | 41 (5.6) | 32 (3.4) | 26 (3.4) | 19 (2.8) |
| HRs | ||||
| Unadjusted | 1.00 | 0.79 (0.58 to 1.07) | 0.64 (0.46 to 0.90) | 0.48 (0.33 to 0.69) |
| Multivariable adjusted 1† | 1.00 | 0.75 (0.53 to 1.08) | 0.76 (0.51 to 1.12) | 0.85 (0.56 to 1.31) |
| Multivariable adjusted 2‡ | 1.00 | 0.85 (0.60 to 1.21) | 0.87 (0.57 to 1.33) | 1.05 (0.72 to 1.53) |
| Cardiovascular mortality | ||||
| Number of deaths | 66 | 102 | 57 | 34 |
| Mortality rate (SE)* | 15 (2.9) | 12 (2.1) | 6 (1.3) | 6 (1.5) |
| HRs | ||||
| Unadjusted | 1.00 | 0.78 (0.49 to 1.24) | 0.44 (0.25 to 0.75) | 0.40 (0.22 to 0.74) |
| Multivariable adjusted 1† | 1.00 | 0.79 (0.47 to 1.32) | 0.59 (0.31 to 1.10) | 0.86 (0.46 to 1.63) |
| Multivariable adjusted 2‡ | 1.00 | 0.96 (0.56 to 1.64) | 0.76 (0.40 to 1.46) | 1.06 (0.56 to 2.00) |
| Cancer mortality | ||||
| Number of deaths | 19 | 64 | 30 | 19 |
| Mortality rate (SE)* | 6 (2.9) | 9 (1.7) | 9 (2.5) | 3 (1.2) |
| HRs | ||||
| Unadjusted | 1.00 | 1.50 (0.52 to 4.36) | 1.52 (0.52 to 4.46) | 0.57 (0.14 to 2.38) |
| Multivariable adjusted 1† | 1.00 | 1.41 (0.47 to 4.18) | 1.74 (0.60 to 5.05) | 0.98 (0.23 to 4.12) |
| Multivariable adjusted 2‡ | 1.00 | 1.73 (0.54 to 5.60) | 1.90 (0.61 to 5.90) | 1.39 (0.32 to 5.99) |
| Diabetes mortality | ||||
| Number of deaths | 63 | 107 | 56 | 31 |
| Mortality rate (SE)* | 18 (4.4) | 12 (1.7) | 8 (1.3) | 5 (1.3) |
| HRs | ||||
| Unadjusted | 1.00 | 0.65 (0.38 to 1.13) | 0.43 (0.25 to 0.74) | 0.28 (0.13 to 0.59) |
| Multivariable adjusted 1† | 1.00 | 0.64 (0.36 to 1.14) | 0.50 (0.27 to 0.91) | 0.43 (0.20 to 0.93) |
| Multivariable adjusted 2‡ | 1.00 | 0.72 (0.40 to 1.30) | 0.67 (0.37 to 1.21) | 0.57 (0.25 to 1.30) |
| Respiratory mortality | ||||
| Number of deaths | 12 | 14 | 13 | 7 |
| Mortality rate (SE)* | 2 (0.4) | 4 (1.3) | 3 (0.9) | 2 (0.8) |
| HRs | ||||
| Unadjusted | 1.00 | 0.47 (0.15 to 1.43) | 0.78 (0.35 to 1.76) | 0.38 (0.11 to 1.30) |
| Multivariable adjusted 1† | 1.00 | 0.45 (0.14 to 1.45) | 1.01 (0.42 to 2.45) | 0.89 (0.27 to 2.90) |
| Multivariable adjusted 2‡ | 1.00 | 0.32 (0.08 to 1.34) | 0.89 (0.34 to 2.36) | 0.85 (0.19 to 3.89) |
*Per 1000 person-years.
†Adjusted for age, race-ethnicity and sex.
‡Adjusted for age, race-ethnicity, sex, smoking status, education, income and diabetes duration.