Table 3

Random effects repeated measures mixed model to predict eGFR, adjusting for baseline eGFR

Independent variableCoefficient (95% CI)p ValueCoefficient (95% CI)p Value
ExposureExposure×time interactions
 0.81–1.0 mmol/L (group 2)0.23 (−1.75 to 2.24)0.814Group 2×time 1−1.16 (−3.42 to 1.10)0.314
 1.01–1.2 mmol/L (group 3)2.78 (−2.11 to 7.68)0.266Group 2×time 2−0.57 (−2.72 to 1.58)0.603
 1.21–2.0 mmol/L (group 4) 0.43 (−3.48 to 4.44)0.834Group 3×time 1−5.18 (−10.3 to −0.08)0.047
TimeGroup 3×time 2−1.91 (−7.13 to 3.31)0.473
 ≤3 months (time 1)−0.35 (−2.17 to 1.47)0.705Group 4×time 1−4.45 (−8.70 to −0.19)0.040
 6 months (±3 months)(time 2) 0.83 (−0.82 to 2.50)0.322Group 4×time 2−2.29 (−6.61 to 2.02)0.298
  • eGFR, estimated-glomerular filtration rate.