Table 2

Trial assessment schedule

Visit 1Visit 2Visit 3Visit 4Visit 5Visit 6Visit 7Visit 8Visit 9Visit 10
ProceduresScreenWeek 0Week 6Week 13Week 26Week 39Week 52Week 65Week 78Week 82
Informed consentX
SMMSEX
NINCDS/ADRDAX
Medical historyX
Neurological examinationX
Physical examinationXX
ECGX
Sitting & standing blood pressureXXXXXXXXX
Clinical laboratory blood testXX
Concomitant MedicationsXXXXXXXXX
Adverse eventsXXXXXXXX
Weight/heightXX
ADAS-Cog 12; CDR-sb, DADXXXX
Dispense drugXXXXXX
Med complianceXXXXXXX
Terminate treatmentX
  • ADAS-Cog 12, Alzheimer's disease Assessment Scale–cognitive subscale; CDR-sb, Clinical Dementia Rating Scale Sum of Boxes; DAD, Disability Assessment for Dementia; NINCDS/ADRDA, National Institute of Neurological and Communicative Disorders and Stroke/Alzheimer's disease and Related Disorders Association; SMMSE, Standardised Mini-Mental State Examination.