Serum biomarker models predicting pulmonary artery/aorta ≥0.92
| Model | Analytes | Crude | Adjusted* | ||
|---|---|---|---|---|---|
| OR (95% CI) | p Value | OR (95% CI) | p Value | ||
| Univariable | MDC | 1.70 (0.90 to 3.19) | 0.100 | 1.78 (0.93 to 3.37) | 0.080 |
| sE-selectin | 1.18 (0.97 to 1.44) | 0.093 | 1.20 (0.98 to 1.47) | 0.075 | |
| tPAI-1 | 0.92 (0.84 to 1.01) | 0.093 | 0.93 (0.85 to 1.03) | 0.148 | |
| Multivariable | MDC | 1.99 (1.02 to 3.88) | 0.043 | 2.08 (1.05 to 4.11) | 0.036 |
| sE-selectin | 1.32 (1.05 to 1.65) | 0.018 | 1.33 (1.06 to 1.68) | 0.016 | |
| tPAI-1 | 0.87 (0.78 to 0.97) | 0.013 | 0.88 (0.79 to 0.98) | 0.024 | |
Per 1 ng/mL MDC, per 10 ng/mL sE-selectin, tPAI-1.
X2 (5)=15.69, p=0.008. Hosmer–Lemeshow's goodness-of-fit test p=0.25.
Area under the receiver operating characteristic curve=0.728 (0.623–0.834).
*Adjusted for age at the CT and exposure group. MDC, macrophage derived chemokine; sE-selectin, soluble endothelial selectin; tPAI, total plasminogen activator inhibitor.