Comparison of age standardised incidence rates (95% CI) per 1000 person years for outcomes on CPRD versus QResearch database in women
| Outcome | CPRD | QResearch | ||||||
|---|---|---|---|---|---|---|---|---|
| Source for case identification | Cases | Ascertainment (%) | Standardised rates per 1000 person years (95% CI) | Cases | Ascertainment (%) | Standardised rates per 1000 person years (95% CI) | Ratio of CPRD to QR standardised rate | |
| Type 2 diabetes | GP data | 48 143 | 99.88 | 4.13 (4.10 to 4.17) | 102 544 | 99.93 | 4.33 (4.31 to 4.36) | 0.95 |
| GP or ONS | 48 203 | NA | 4.13 (4.10 to 4.17) | 102 618 | NA | 4.34 (4.31 to 4.36) | 0.95 | |
| Ischaemic stroke | GP data | 32 283 | 90.64 | 2.45 (2.42 to 2.48) | 63 582 | 90.22 | 2.45 (2.44 to 2.47) | 1.00 |
| GP or ONS | 35 617 | NA | 2.62 (2.59 to 2.64) | 70 477 | NA | 2.70 (2.68 to 2.72) | 0.97 | |
| Cardiovascular disease | GP data | 55 833 | 85.71 | 5.41 (5.37 to 5.46) | 107 412 | 84.96 | 4.32 (4.30 to 4.35) | 1.25 |
| GP or ONS | 65 143 | NA | 6.32 (6.27 to 6.37) | 126 433 | NA | 5.03 (5.01 to 5.06) | 1.26 | |
| GP or ONS or HES | 69 202 | NA | 6.72 (6.67 to 6.77) | 140 510 | NA | 5.63 (5.60 to 5.66) | 1.19 | |
| Thromboembolism | GP data | 18 199 | 91.1 | 1.52 (1.49 to 1.54) | 35 971 | 90.55 | 1.46 (1.44 to 1.47) | 1.04 |
| GP or ONS | 19 978 | NA | 1.64 (1.62 to 1.67) | 39 727 | NA | 1.60 (1.58 to 1.62) | 1.03 | |
| Fractured neck of femur | GP data | 17 529 | 99.98 | 1.32 (1.30 to 1.34) | 34 821 | 99.99 | 1.40 (1.39 to 1.42) | 0.94 |
| GP or ONS | 17 533 | NA | 1.32 (1.30 to 1.34) | 34 825 | NA | 1.40 (1.39 to 1.42) | 0.94 | |
| Osteoporotic fracture | GP data | 34 528 | NA | 2.89 (2.58 to 3.20) | 81 334 | NA | 3.63 (3.61 to 3.66) | 0.80 |
| Moderate/severe kidney failure | GP data | 19 902 | NA | 2.06 (1.76 to 2.36) | 48 665 | NA | 2.81 (2.78 to 2.83) | 0.73 |
| Severe kidney failure | GP data | 1737 | NA | 0.18 (0.09 to 0.27) | 4150 | NA | 0.24 (0.24 to 0.25) | 0.74 |
CPRD, Clinical Research Data Link; GP, general practitioner; HES, hospital episode statistics; NA, not available; ONS, Office for National Statistics.