Table 4

Numbers of patients eligible for each score in the Clinical Research Data Link validation cohort and number of patients with complete risk factor recording not requiring multiple imputation

Risk scoreClinical outcomeEligible age rangeExclusion criteria at study entryTotal in age rangeTotal with exclusionsTotal eligible for analysisTotal complete dataComplete data (%)
QDiabetesType 2 diabetes25–84Type 1 or 2 diabetes at study entry3 177 19299 1893 078 0032 467 64280.2
QStrokeIschaemic stroke25–84Existing stroke or anticoagulants at study entry3 177 19270 9613 106 2311 032 18433.2
QRISK2CVD25–84Existing CVD or statins at study entry3 177 192232 7222 944 470906 78130.8
QThrombosisThromboembolism25–84Existing VTE or anticoagulants at study entry3 177 19253 9043 123 2882 513 34780.5
QFractureFractured neck of femur30–99None except age2 852 38102 852 3812 087 14973.2
QFractureOsteoporotic fracture30–99None except age2 852 38102 852 3812 087 14973.2
QKidneyModerate or severe kidney failure35–74Existing moderate or severe kidney failure2 069 57210 5182 059 0541 146 61955.7
QKidneySevere kidney failure35–74Existing severe kidney failure2 069 57219302 067 6421 153 97955.8
QBleedUpper gastrointestinal bleed*25–99Anticoagulants in 180 days prior to study entry2 429 69635 2832 394 4131 890 80479.0
QBleedIntracranial bleed*25–99Anticoagulants in 180 days prior to study entry2 429 69635 2832 394 4131 890 80479.0
  • *Entry date was 1 January 1998 except for upper gastrointestinal bleed and intracranial bleed where entry date was 1 January 2007.

  • CVD, cardiovascular disease; VTE, venous thromboembolism.