Table 3

Results from linear regression analyses of semen quality (adjusted β-coefficients) and serum reproductive hormones (percent change) among young, Danish men according to habitual alcohol intake (last week represented a typical week) or recent (the week preceding the visit) or binging during the past 30 days

Alcohol intakeNSperm concentration*† (million/mL)Total sperm count*† (million)Morphology†‡ (%)NTestosterone§¶ (nmol/L)SHBG§¶ (nmol/L)Free testosterone§¶ (pmol/L)
Β95% CIβ95% CIβ95% CI%95% CI%95% CI%95% CI
Units in a typical week, N=553Units the week preceding the visit, N=1194
 0121−0.32−0.62 to −0.03−0.42−0.86 to 0.01−0.21−0.54 to 0.12242−2.7−8.5 to 3.5−0.6−8.6 to 6.9−3.3−9.1 to 2.6
 1–592ReferenceReferenceReference193ReferenceReferenceReference
 6–1071−0.04−0.38 to 0.3−0.06−0.56 to 0.45−0.12−0.49 to 0.261543.3−3.6 to 10.6−3.0−10.6 to 5.25.5−1.4 to 12.9
 11–1580−0.21−0.54 to 0.12−0.29−0.77 to 0.20−0.19−0.56 to 0.181602.0−4.9 to 9.2−3.1−10.6 to 5.13.6−3.1 to 10.7
 16–2062−0.03−0.39 to 0.33−0.18−0.70 to 0.34−0.09−0.46 to 0.291303.0−4.2 to 10.8−2.1−10.1 to 6.74.3−3.0 to 12.0
 21–25450.25−0.15 to 0.650.07−0.52 to 0.65−0.13−0.55 to 0.29927.3−1.1 to 16.4−0.2−9.4 to 9.97.9−0.3 to 16.9
 26–3025−0.35−0.83 to 0.14−0.65−1.37 to 0.08−0.19−0.71 to 0.34711.0−7.7 to 10.4−9.0−18.1 to 1.15.9−3.1 to 15.5
 31–3514−0.29−0.92 to 0.33−0.60−1.51 to 0.31−0.56−1.19 to 0.06476.1−4.5 to 17.8−9.8−20.3 to 2.111.90.8 to 23.9
 36–4011−0.33−1.02 to 0.35−0.73−1.73 to 0.28−0.54−1.20 to 0.13289.1−4.2 to 17.8−9.3−22.2 to 5.716.02.1 to 31.7
 >4021−0.39−0.92 to 0.14−0.54−1.32 to 0.23−0.46−0.99 to 0.086610.60.8 to 21.3−12.0−21.1 to −1.919.59.2 to 30.9
 p trend**0.020.010.020.01<0.01<0.01
Number of binge episodes during the past 30 days††
 0174ReferenceReferenceReference171ReferenceReferenceReference
 1–2248−0.01−0.23 to 0.220.15−0.18 to 0.480.07−0.16 to 0.312464.0−2.5 to 10.87.90.1 to 16.41.0−5.2 to 7.6
 3–54070.08−0.13 to 0.290.26−0.05 to 0.560.10−0.12 to 0.314016.20.1 to 12.64.1−2.9 to 11.66.10.1 to 12.4
 6–92530.00−0.23 to 0.230.08−0.26 to 0.41−0.04−0.28 to 0.192528.41.6 to 15.61.1−6.7 to 9.210.23.4 to 17.5
 >988−0.02−0.32 to 0.290.03−0.41 to 0.47−0.22−0.52 to 0.088913.03.8 to 23.1−2.9−12.1 to 7.517.27.8 to 27.6
 p trend**0.930.870.16<0.010.310.01
  • *Adjusted for period of abstinence, smoking and body mass index (BMI) categorised according to table 2 (sperm morphology not adjusted for period of abstinence).

  • †Transformed by cubic root.

  • ‡Counted for 904 men of whom 397 stated that last weeks alcohol intake represented a typical week.

  • §Adjusted to a time at 8.00, BMI and smoking.

  • ¶Transformed by the use of natural logarithm and back transformed giving the percentages change.

  • **Test for trend was performed by inserting the categorical alcohol variable into the model assuming the association to be linear with 1–5 units weekly as reference and 0 units excluded.

  • ††Binging defined as alcohol intake for more than 5 units on one occasion.