Table 6

Comparison of age standardised incidence rates (95% CI) per 1000 person years for outcomes on CPRD versus QResearch database in men

OutcomeCPRDQResearch
Source for case identificationCasesAscertainment (%)Standardised rates per 1000 person years (95% CI)CasesAscertainment (%)Standardised rates per 1000 person years (95% CI)Ratio of CPRD to QR standardised rate
Type 2 diabetesGP data60 73199.925.84 (5.79 to 5.89)128 23499.945.97 (5.94 to 6.00)0.98
GP or ONS60 782NA5.84 (5.80 to 5.89)128 317NA5.98 (5.94 to 6.01)0.98
Ischaemic strokeGP data32 22393.553.17 (3.14 to 3.20)63 48092.853.10 (3.08 to 3.13)1.02
GP or ONS34 443NA3.33 (3.30 to 3.37)68 366NA3.37 (3.34 to 3.40)0.99
Cardiovascular diseaseGP data70 28386.77.38 (7.33 to 7.44)137 13686.127.12 (7.08 to 7.16)1.03
GP or ONS81 068NA8.52 (8.46 to 8.58)159 240NA8.37 (8.33 to 8.41)1.02
GP or ONS or HES84 620NA8.90 (8.84 to 8.96)174 405NA9.17 (9.13 to 9.21)0.97
ThromboembolismGP data15 65592.321.49 (1.46 to 1.51)31 50392.221.44 (1.43 to 1.46)1.03
GP or ONS16 958NA1.61 (1.59 to 1.63)34 161NA1.57 (1.56 to 1.59)1.02
Fractured neck of femurGP data5,70699.980.65 (0.63 to 0.67)12 43599.980.71 (0.70 to 0.73)0.91
GP or ONS5,707NA0.65 (0.63 to 0.67)12 438NA0.71 (0.70 to 0.73)0.91
Osteoporotic fractureGP data11 169NA1.29 (1.05 to 1.52)28 555NA1.54 (1.52 to 1.55)0.84
Moderate/severe kidney failureGP data37 597NA4.88 (4.37 to 5.38)86 649NA5.82 (5.78 to 5.85)0.84
Severe kidney failureGP data3472NA0.54 (0.38 to 0.71)7372NA0.47 (0.46 to 0.48)1.15
  • CPRD, Clinical Research Data Link; GP, general practitioner; HES, hospital episode statistics; NA, not available; ONS, Office for National Statistics.