Clinical characteristics of patients with AP and healthy individuals
| MAP (n=80) | SAP (n=26) | Healthy individuals (n=204) | p Value | |
|---|---|---|---|---|
| Age (years) | 48.2±14.7* | 60.5±14.5† | 48.0±11.7 | <0.001‡ |
| Gender (M/F) | 41/39 | 11/15 | 102/102 | 0.722§ |
| AP hospital stay (days) | 14 (6–75) | 14.5 (2–52) | ||
| AP mortality | 0 | 8 | ||
| BUN (mmol/L) | 4.8 (2–17.5) | 4.9 (2.6–15.2) | 5.6 (2.7–8.6) | 0.208¶ |
| Cr (μmol/L) | 52 (35–193)† | 59 (37–198) | 65 (33–121) | <0.001¶ |
| TB (μmol/L) | 18 (6–90)† | 17 (9–92)† | 13 (6–45) | <0.001¶ |
| ALT (U/L) | 35 (7–235)† | 33 (15–591)† | 18.5 (8–85) | <0.001¶ |
| AST(U/L) | 28.5 (12–129)† | 31 (15–1989)† | 21 (13–45) | <0.001¶ |
| Ca (mmol/L) | 2.11±0.24*† | 2.03±0.19† | 2.31±0.08 | <0.001‡ |
| Amy (U/L) | 934 (28–3734)*† | 506 (28–2277) † | 45 (22–110) | <0.001¶ |
| TP (g/L) | 59.2±9.05† | 58.5±8.00† | 74.1±3.5 | <0.001‡ |
| Alb (g/L) | 36.2±7.15*† | 34.0±4.64† | 48.3±2.3 | <0.001‡ |
| LDH (U/L) | 306.8±148.3*† | 400.2±207.9† | 185.0±32.2 | <0.001‡ |
| Glu (mmol/L) | 7.30±3.04† | 6.83±1.20† | 5.21±0.68 | <0.001‡ |
| WCC (×109/L) | 12.2 (2.7–33.9)† | 8.9 (4.6–32.0)† | 6.3 (4.1–9.5) | <0.001¶ |
| RBC (×1012/L) | 4.85±0.67*† | 4.15±1.07† | 4.59±0.46 | <0.001‡ |
| Hgb (g/L) | 147±20* | 123±29† | 144±15 | <0.001‡ |
| PLT (×109/L) | 210±76 | 181±119† | 216±64 | 0.069‡ |
| RDW (%) | 12.6±0.59*† | 14.4±1.06† | 13.42±0.85 | <0.001‡ |
| MCV (fL) | 88.60±4.32† | 89.6±4.74† | 92.82±5.05 | <0.001‡ |
| MPV (fL) | 11.05±1.27*† | 11.58±1.20† | 8.82±1.12 | <0.001‡ |
*p<0.05, MAP compared with SAP.
†p<0.05, patients with MAP and SAP compared with healthy individuals.
‡Analysis of variance.
§χ2 Test.
¶Kruskal-Wallis H test.
Alb, albumin; ALT, alanine aminotransferase; Amy, elevated serum amylase; AP, acute pancreatitis; AST, aspartate aminotransferase; BUN, blood urea nitrogen; Ca, calcium; Cr, creatinine; F, female; Glu, glucose; Hgb, haemoglobin; LDH, lactate dehydrogenase; M, male; MAP, mild acute pancreatitis; MCV, mean corpuscular volume; MCV, mean corpuscular volume; MPV, mean platelet volume; PLT, platelet; RBC, red blood cell; RDW, red cell distribution width; SAP, severe acute pancreatitis; TB, total bilirubin; TP, total protein; WCC, white cell count.