TableĀ 2

Quality assessment of randomised controlled trials using tools adapted from the Delphi list

Sequence generationIs the method of sequence generation clearly reported?Yes/no/unclear
Allocation concealmentIs treatment allocation concealment (using an opaque envelope, central allocation) performed?Yes/no/unclear
Baseline characteristicsAre the groups similar at baseline regarding the most important prognostic factors?Yes/no/unclear
Eligibility criteriaAre eligibility criteria clearly specified?Yes/no/unclear
Blindness to outcome assessorIs the outcome (mortality) assessor blinded?Yes/no/unclear
Blindness to care providerIs the allocation unknown to the treating physician?Yes/no/unclear
Blindness to patientIs the patient blinded?Yes/no/unclear
Point estimate and variabilityAre the point estimate and variability reported for the outcome measure?Yes/no/unclear
Intention-to-treatDoes the analysis include intention to treat analysis?Yes/no/unclear