Table 3

Determinants of persistent or chronic respiratory symptoms at the end of tuberculosis treatment

FactorsCrude OR (95% CI)p ValueAdjusted OR (95% CI)p Value
Male sex1.31 (0.71 to 2.44)0.387//
Age1.01 (0.98 to 1.03)0.646//
Duration of symptoms >12 weeks3.31 (1.29 to 8.50)0.0132.91 (1.12 to 7.60)0.029
Smoking1.68 (0.75 to 3.76)0.209//
Previous pulmonary tuberculosis1.86 (0.69 to 4.98)0.218//
HIV infection0.76 (0.39 to 1.51)0.439//
Extension of pulmonary lesions >4 zones1.48 (0.71 to 3.07)0.292//
Cavitary disease1.12 (0.57 to 2.20)0.751//
Fibrotic lesions1.24 (0.59 to 2.62)0.571//
FEF25–75%2.45 (1.26 to 4.77)0.008//
 ≥80%1 (reference)/
 65%–79%1.39 (0.61 to 3.13)0.433//
 <65%2.72 (1.33 to 5.54)0.0062.22 (1.13 to 4.38)0.021
  • FEF25–75%, forced expiratory flow between 25% and 75% of forced vital capacity.