Table 3

Number of deaths, suicide-related and homicide-related events, and psychiatric serious adverse events in drug-treated participants

DeathSuicide, completedSuicidal ideation, attempts, injuryHomicidal ideationNew or worsened psychiatric symptomsTotal
Aripiprazole
 Trial summary (n=28)7914079163
 Journal article (n=28)27 (34.2)*1 (100.0)5 (125.0)066 (83.5)99 (60.7)
 Unpublished trial summary† (n=21)15110092118
Olanzapine
 Trial summary (n=33)50918085162
 Journal article (n=33)19 (38.0)1 (11.1)4 (22.2)014 (16.5)38 (23.5)
 Unpublished trial summary (n=18)7321195127
Ziprasidone
 Trial summary (n=8)011313045
 Journal article (n=8)0 (0)1 (100.0)5 (38.5)1 (100.0)14 (46.7)20 (44.4)
 Unpublished trial summary (n=21)181233141186
Atomoxetine
 Trial summary (n=31)0070613
 Journal article (n=31)000 (0)00 (0)0 (0)
 Unpublished trial summary (n=20)1050511
Duloxetine
 Trial summary (n=35)1144002782
 Journal article (n=35)11 (100.0)4 (100.0)33 (82.5)021 (77.8)69 (84.1)
 Unpublished trial summary (n=13)301002033
Sertraline
 Trial summary (n=7)110501127
 Journal article (n=7)0 (0)00 (0)0 (0)0 (0)0 (0)
 Unpublished trial summary (n=9)10101416
All Drugs
 Trial summary (n=142)15115871238492
 Journal article (n=142)57 (37.7)7 (46.7)47 (54.0)1 (100.0)115 (48.3)227 (46.1)
 Unpublished trial summary (n=102)455795357491
  • *Percent as reported in associated trial summaries.

  • †Unpublished trial summary refers to clinical trial summaries posted on the publicly accessible clinicalstudyresults.org website, but having no associated stand-alone journal article.