Demographic and clinical characteristics
N | 49 |
Age, year, mean (SD) | 54 (11), range 25–72 |
Female gender, % | 69 |
Education, year, mean (SD) | 16 (2) |
Family history of LOAD, % positive | 69 |
APOE ε4 status*, % positive | 39 |
Ethnicity, % | |
White | 82 |
Black | 8 |
Hispanic | 6 |
Other | 4 |
Body mass index (unitless), mean (SD) | 26 (4) |
Hip-to-waist ratio (unitless), mean (SD) | 1.2 (0.2) |
Blood pressure (mm/Hg), mean (SD) | |
Systolic | 118 (15) |
Diastolic | 71 (9) |
Glucose (mg/dL) | 78 (12) |
Cholesterol (mg/dL) | 200 (38) |
HDL (mg/dL) | 62 (19) |
LDL (mg/dL) | 119 (33) |
Triglycerides (mg/dL) | 91 (40) |
Homocystein (μmol/L) | 10 (2) |
Neuropsychological tests, mean (SD) | |
Mini-Mental State Examination | 29 (1) |
Digit symbol substitution | 62 (10) |
Paired associates delayed recall | 7 (2) |
Paragraph delayed recall | 10 (3) |
Designs | 8 (2) |
Object naming | 55 (12) |
WAIS-vocabulary | 65 (14) |
Nutrients levels, mean (SD), range | |
β-carotene (μg) | |
Foods | 6556 (8593), 825–25 451 |
Foods and supplements | 7438 (8447), 1331–25 957 |
ω-3 polyunsaturated fatty acid (g) | |
Foods | 0.19 (0.14), 0.05–0.82 |
Foods and supplements | 0.23 (0.18), 0.08–1.09 |
ω-6 polyunsaturated fatty acid (g) | |
Foods | 19.7 (17.3), 5.2–75.5 |
Foods and supplements | 20.1 (17.2), 5.3–75.5 |
Folate (μg) | |
Foods | 486.6 (345.1), 181.4–1674.2 |
Foods and supplements | 648.1 (335.9), 187.6–1759.9 |
Monounsaturated fats (g) | |
Foods | 38.7 (31.5), 10.8–164.5 |
Foods and supplements | n.a. |
Saturated fats (g) | |
Foods | 23.5 (13.0), 8.6–61.3 |
Foods and supplements | n.a. |
Vitamin B12 (μg) | |
Foods | 4.5 (2.7), 1.3–12.1 |
Foods and supplements | 15.4 (9.9), 2.6–58.3 |
Vitamin C (mg) | |
Foods | 129 (100), 35–521 |
Foods and supplements | 305 (267), 69–1565 |
Vitamin D (μg) | |
Foods | 4.7 (2.9), 1.1–16.3 |
Foods and supplements | 729 (445), 1.8–1806 |
Vitamin E (mg) | |
Foods | 13.2 (11.5), 3.6–57.4 |
Foods and supplements | 697 (37), 632–797 |
*APOE genotyping was obtained from 41/49 participants.
APOE, apolipoprotein E; HDL, high-density lipoprotein; LDL, low-density lipoprotein.