Table 1

Demographic and clinical characteristics

N49
Age, year, mean (SD)54 (11), range 25–72
Female gender, %69
Education, year, mean (SD)16 (2)
Family history of LOAD, % positive69
APOE ε4 status*, % positive39
Ethnicity, %
 White82
 Black8
 Hispanic6
 Other4
Body mass index (unitless), mean (SD)26 (4)
Hip-to-waist ratio (unitless), mean (SD)1.2 (0.2)
Blood pressure (mm/Hg), mean (SD)
 Systolic118 (15)
 Diastolic71 (9)
Glucose (mg/dL)78 (12)
Cholesterol (mg/dL)200 (38)
HDL (mg/dL)62 (19)
LDL (mg/dL)119 (33)
Triglycerides (mg/dL)91 (40)
Homocystein (μmol/L)10 (2)
Neuropsychological tests, mean (SD)
 Mini-Mental State Examination29 (1)
 Digit symbol substitution62 (10)
 Paired associates delayed recall7 (2)
 Paragraph delayed recall10 (3)
 Designs8 (2)
 Object naming55 (12)
 WAIS-vocabulary65 (14)
Nutrients levels, mean (SD), range
 β-carotene (μg)
  Foods6556 (8593), 825–25 451
  Foods and supplements7438 (8447), 1331–25 957
 ω-3 polyunsaturated fatty acid (g)
  Foods0.19 (0.14), 0.05–0.82
  Foods and supplements0.23 (0.18), 0.08–1.09
 ω-6 polyunsaturated fatty acid (g)
  Foods19.7 (17.3), 5.2–75.5
  Foods and supplements20.1 (17.2), 5.3–75.5
 Folate (μg)
  Foods486.6 (345.1), 181.4–1674.2
  Foods and supplements648.1 (335.9), 187.6–1759.9
 Monounsaturated fats (g)
  Foods38.7 (31.5), 10.8–164.5
  Foods and supplementsn.a.
 Saturated fats (g)
  Foods23.5 (13.0), 8.6–61.3
  Foods and supplementsn.a.
 Vitamin B12 (μg)
  Foods4.5 (2.7), 1.3–12.1
  Foods and supplements15.4 (9.9), 2.6–58.3
 Vitamin C (mg)
  Foods129 (100), 35–521
  Foods and supplements305 (267), 69–1565
 Vitamin D (μg)
  Foods4.7 (2.9), 1.1–16.3
  Foods and supplements729 (445), 1.8–1806
 Vitamin E (mg)
  Foods13.2 (11.5), 3.6–57.4
  Foods and supplements697 (37), 632–797
  • *APOE genotyping was obtained from 41/49 participants.

  • APOE, apolipoprotein E; HDL, high-density lipoprotein; LDL, low-density lipoprotein.