Table 2

Adjusted ORs for outcomes associated with admission to either tertiary or high-volume neonatal care at the hospital of birth using a ‘standard’ logistic regression model

Tertiary neonatal unitHigh-volume neonatal unit†
Outcome(1)
≤32+6 weeks
(2)
≤26+6 weeks
(3)
27+0–32+6 weeks
(4)
≤32+6 weeks
(5)
≤26+6 weeks
(6)
27+0–32+6 weeks
Neonatal mortality0.77 (0.59 to 1.00)0.65* (0.46 to 0.91)0.92 (0.69 to 1.22)0.73* (0.56 to 0.95)0.62** (0.44 to 0.87)0.86 (0.65 to 1.14)
Any in-hospital mortality0.91 (0.72 to 1.15)0.78 (0.57 to 1.06)1.06 (0.83 to 1.36)0.83 (0.65 to 1.05)0.71* (0.52 to 0.97)0.96 (0.75 to 1.24)
BPD1.23** (1.07 to 1.40)1.50** (1.11 to 2.01)1.17 (0.99 to 1.39)1.11 (0.97 to 1.28)1.59** (1.18 to 2.14)1.02 (0.86 to 1.22)
Treatment for ROP1.26 (0.91 to 1.75)1.09 (0.76 to 1.57)1.52 (0.91 to 2.55)0.95 (0.68 to 1.32)0.81 (0.56 to 1.17)1.22 (0.71 to 2.09)
Surgery for NEC1.05 (0.76 to 1.44)0.89 (0.58 to 1.36)1.17 (0.80 to 1.70)1.05 (0.76 to 1.45)0.94 (0.62 to 1.45)1.11 (0.76 to 1.61)
PMA at discharge >40 weeks1.17 (0.97 to 1.41)1.09 (0.87 to 1.37)1.19 (0.97 to 1.47)1.13 (0.94 to 1.37)1.11 (0.89 to 1.38)1.11 (0.90 to 1.37)
  • Values are ORs (95% CI).

  • Models are adjusted for gestational age, gestational age squared, birthweight z-score, use of antenatal steroids, gender, infant year of birth and deprivation.

  • *p<0.05, **p<0.01, ***p<0.001.

  • †High volume was defined as being in the top quartile of units by number of care days provided to infants born at ≤32+6 weeks gestation.

  • BPD, bronchopulmonary dysplasia; NEC, necrotising enterocolitis; PMA, postmenstrual age; ROP, retinopathy of prematurity.