Table 2

Sensitivity and subgroup analyses

	Number of arms	Mean age (years)*	Mean basal HbA1c (%)*	Pooled differences T₂–T₁ HbA1c (%) (95% CI)	p Value	I² (%)	I² p value
Correlation 0.50	12	62.2	7.96	0.22 (0.15 to 0.29)	<0.0001	91	<0.0001
Correlation 0.25	12	62.2	7.96	0.21 (0.14 to 0.29)	<0.0001	86	<0.0001
Correlation 0.75	12	62.2	7.96	0.22 (0.15 to 0.29)	<0.0001	95	<0.0001
Primary studies†	6	63	7.93	0.19 (0.13 to 0.25)	<0.0001	86	<0.0001
Extension studies†	6	54.8	8.22	0.24 (0.02 to 0.46)	0.036	92	<0.0001
Metformin (add-on to)†	5	57.8	7.62	0.24 (0.16 to 0.32)	<0.0001	82	<0.0001

*Mean value weighted by sample size.
†Assuming a 0.50 correlation.