Multivariable Cox regression models analysing the association between the marital status at the time of diagnosis and mortality after oesophagectomy for cancer, expressed as HRs with 95% CIs
| Marital status | ||||
|---|---|---|---|---|
| Married (reference) | Remarried HR (95% CI) | Previously married* HR (95% CI) | Never married HR (95% CI) | |
| Overall 5-year mortality | ||||
| Model 1 | 1 | 0.77 (0.54 to 1.10) | 1.09 (0.87 to 1.37) | 1.14 (0.87 to 1.49) |
| Model 2 | 1 | 0.79 (0.55 to 1.13) | 0.95 (0.75 to 1.20) | 1.03 (0.78 to 1.36) |
| Model 3 | 1 | 0.79 (0.55 to 1.13) | 0.90 (0.71 to 1.15) | 1.02 (0.77 to 1.35) |
| Conditional† overall 5-year mortality | ||||
| Model 1 | 1 | 0.73 (0.50 to 1.07) | 1.11 (0.87 to 1.41) | 1.18 (0.89 to 1.57) |
| Model 2 | 1 | 0.73 (0.50 to 1.08) | 0.96 (0.75 to 1.23) | 1.04 (0.78 to 1.38) |
| Model 3 | 1 | 0.74 (0.50 to 1.08) | 0.93 (0.72 to 1.20) | 1.05 (0.78 to 1.41) |
| Disease-specific‡ 5-year mortality | ||||
| Model 1 | 1 | 0.79 (0.56 to 1.13) | 1.11 (0.88 to 1.40) | 1.19 (0.89 to 1.57) |
| Model 2 | 1 | 0.80 (0.56 to 1.15) | 0.96 (0.76 to 1.22) | 1.03 (0.77 to 1.34) |
| Model 3 | 1 | 0.80 (0.56 to 1.15) | 0.92 (0.72 to 1.17) | 1.04 (0.78 to 1.39) |
| Conditional† disease-specific‡ 5-year mortality | ||||
| Model 1 | 1 | 0.75 (0.51 to 1.10) | 1.12 (0.87 to 1.43) | 1.21 (0.90 to 1.63) |
| Model 2 | 1 | 0.74 (0.50 to 1.09) | 0.97 (0.76 to 1.25) | 1.02 (0.76 to 1.38) |
| Model 3 | 1 | 0.74 (0.51 to 1.10) | 0.94 (0.73 to 1.22) | 1.05 (0.78 to 1.42) |
Values are expressed as HRs.
*Previously married was defined as patients who have been married before but are living alone (after the death of the partner or divorce).
†Conditional mortality: excluding first 90 days after surgery.
‡Disease-specific mortality: oesophageal or junctional cancer as the underlying or contributing cause. Model 1: unadjusted. Model 2: adjusted for sex, age, tumour stage. Model 3: adjusted for sex, age, tumour stage, histology, major complications, comorbidity and surgeon volume.