Table 4

Crude and adjusted ORs for asthma in children prenatally exposed to corticosteroids compared with unexposed siblings.

NModel 1
OR (95% CI)
Model 2
OR (95% CI)
Unexposed children (at least one sibling has been prenatally exposed)59571.00 (ref)1.00 (ref)
Exposed children (at least one sibling has been prenatally unexposed)45421.12 (1.00 to 1.24)1.11 (0.98 to 1.25)
  • Model 1: the estimate is adjusted for birth year (1996–2000, 2001–2005, 2006–2009).

  • Model 2: the estimate is additionally adjusted for maternal age, maternal smoking status, maternal use of medication (paracetamol, proton-pump inhibitors, cyclooxygenase inhibitors, antibiotics), mode of delivery, gestational age, birth order, birth weight, gender and birth year.