Table 1

Characteristics of mothers of live-born children from 1 January 1996 to 31 December 2009 in Denmark according to corticosteroid drug use during pregnancy (N=877 778)

CharacteristicsCorticosteroid use during pregnancy, n (%)No corticosteroid use during pregnancy, n (%)
All31 759 (100)846 019 (100)
Age at giving birth (years)
 <252363 (7.4)119 386 (14.1)
 25–299306 (29.3)295 693 (35.0)
 30–3412 819 (40.4)295 891 (35.0)
 35–396170 (19.4)116 104 (13.7)
 ≥401 101 (3.5)18 945 (2.2)
Use of other drugs during pregnancy
 Antibiotics14 817 (46.7)297 906 (35.2)
 Paracetamol554 (1.7)5367 (0.6)
 PPIs887 (2.8)10 238 (1.2)
 NSAIDs/Coxibs2384 (7.5)35 412 (4.2)
Smoking during pregnancy
 No25 391 (80.0)653 391 (77.2)
 1–10 cigarettes/day3908 (12.3)120 435 (14.2)
 11–20 cigarettes/day1150 (3.6)35 206 (4.2)
 >20 cigarettes/day173 (0.5)4962 (0.6)
 Missing1137 (3.6)32 025 (3.8)
Chronic disease
 Inflammatory bowel disease (IBD)1037 (3.3)5097 (0.6)
 Crohn's disease (CD)251 (0.8)1775 (0.2)
 Ulcerative colitis (UC)655 (2.1)2793 (0.3)
 Both131 (0.4)529 (0.1)
 Chronic obstructive pulmonary disease (COPD)178 (0.6)2159 (0.3)
 Maternal diabetes mellitus (type 1)116 (0.4)2865 (0.3)
 Maternal diabetes mellitus (type 2)120 (0.4)2355 (0.3)
 Asthma4431 (14.0)38 662 (4.6)
Maternal body mass index (BMI) *
 Low553 (1.7)16 854 (2.0)
 Normal8846 (27.9)204 289 (24.1)
 Overweight3131 (9.9)68 411 (8.1)
 Obese and severe obesity1716 (5.4)38 215 (4.5)
  • *Data on maternal BMI were only available from 2004 onward.

  • NSAIDS, non-steroidal anti-inflammatory drugs; Coxibs, cyclooxygenase inhibitors.