Table 1

Demographics of the PoTS UK cohort compared with the PoTS clinic cohort

PoTS UKPoTS clinicp ValueTotal PoTS
N8452136
Age, mean±SD32±1036±110.0433±10
Males, n (%)3 (4)10 (19)0.00513 (10)
BMI, mean±SD24±534±50.0927±5
Smokers, n (%)12 (14)2 (4)0.0814 (10)
Previous smoker, n (%)14 (17)6 (12)0.520 (15)
Alcohol, yes, n (%)28 (33)20 (38)0.648 (35)
Caffeine, yes, n (%)46 (55)34 (65)0.380 (59)
Drugs, yes, n (%)4 (5)00.34 (3)
Age symptoms started, mean±SD23±10 n=7628±12 n=500.0124±11
Age diagnosed, mean±SD30±10 n=8233±11 n=480.0931±10
Difference, mean±SD8.3±10 n=795.2±5 n=490.046.7±7
Symptoms assessment tools
 Fatigue Impact Scale91±3292±370.892±34
 Epworth Sleepiness Scale10±510±80.810±5
 Orthostatic Grading Scale13±412±40.413±4
 Hospital Anxiety and Depression14±715±90.315±7
 Patient Reported Outcome Measure Health Assessment Questionnaire26±2126±221.026±21
 Cognitive Failures Questionnaire50±2451±230.751±23
Comorbidity
 Chronic Fatigue Syndrome6 (7)22 (42)0.000128 (21)
 Ehlers Danlos Syndrome22 (26)2 (4)0.000924 (18)
 Irritable Bowel Syndrome9 (11)5 (10)1.014 (10)
 Thyroid10 (12)3 (6)0.413 (10)
 Heart4 (5)00.34 (3)
 Fibromyalgia7 (8)2 (4)0.59 (7)
Education
 Left school at 169 (11)12 (23)0.0921 (15)
 Left school at 187 (8)5 (10)1.012 (9)
 University degree33 (40)23 (44)0.656 (41)
 Postgraduate degree16 (19)12 (23)0.728 (21)
 Other14 (17)014 (10)
  • BMI, body mass index.