Table 3

Relevant characteristics and neurological signs in cases with parkinsonism with/without cognitive impairment (n=16) in Papua, 2001–2012

Case numberYahr stageSurvey yearVillageAgeSexOnset (age/year)Duration (years)Death (year)EthnicityUMN signsLMN signsBulbar signsParkinsonian signCognitive impairmentFamily history
P 1Yahr IV2001Kepi50MNCNCNCJakai2/2−/−−/−+/++/++++
P 2Yahr II2001Kepi50MNCNCNCJakai2/2−/−−/−+++
P 3Yahr IV2002Emete52M49/'993NCJakai2/2−/−−/−++++
P 4Yahr II2002Senggo41M36/'975NCCitak2/2−/−−/−++
P 5Yahr I2007Mur65F61/'034NCJakai2/3−/−−/−+/−+/−10
P 6Yahr IV2008Pies60F55/'0362009Auyu2/2−/−−/−+/++/++++11
P 7Yahr IV2008/'10Mopio52F47/'055AliveAuyu3/3−/−−/−++/++/++++
P 8Yahr II2011Sien57F49/'0392012Auyu3/3−/−−/−+/++/++12
P 9Yahr IV2007/'08/' 10/'12Bade46F40/'066AliveAuyu3/3−/−−/−+/+++/+++13
P 10Yahr II2011/'12Asset38M27/'0111AliveAuyu3/3−/−−/−+/−+/−+
P 11Yahr III2011/'12Sien54F40/'9814AliveAuyu3/3−/−−/−++/+++/++++
P 12Yahr II2011/'12Memes66F64/'102AliveAuyu3/3−/−−/−+/++/++14
P 13Yahr II2012Harapan60M57/'093AliveAuyu2/2−/−−/−+/+
P 14Yahr II2007Mur50M38/'9512NCAuyu2/4+−/−−/−+++
P 15Yahr I2007Homilikia50MNCNCAliveAuyu2/3+−/−−/−+/−+/±
P 16Yahr III2011Osso35F33/'0922011Auyu3/2−/−−/−+/++/++++15
  • Age: at the time of final survey; Alive: alive in 2012; Deep tendon reflexes: −, absent; 1, hypoactive; 2, normal; 3, hyperactive; 4, markedly hyperactive with ankle clonus; Duration: between subjective onset of illness and last survey or death; Onset: subjective onset of illness.

  • Other signs are classified as: −, absent; ±, questionably present; +, present; ++, markedly present.

  • Family history: 10, son (NC); 11, sister (ALS-P 1) and cousin (NC); 12, mother and father (NC); 13, grandmother (NC); 14, mother (NC); 15, mother's cousin (ALS 10).

  • ALS, amyotrophic lateral sclerosis; BK, bradykinesia; BS, Babinski sign; DTR, deep tendon reflex; Dys, dysphagia/dysarthria; F, female; Fasc, fasciculation; LMN, lower motor neuron signs; M, male; MA, muscle atrophy with weakness; NC, not confirmed by examination; P, parkinsonism; PI, postural impairment; R, rigidity; T, tremor; TA, tongue atrophy; U/L, upper limbs/lower limbs; UMN, upper motor neuron signs; Yahr stage, the scale of Hoehn and Yahr.