Multivariate analyses for SVT
| Age–sex adjusted* OR (p value) | Fully adjusted OR (p value) | Final model OR (p value) | |
|---|---|---|---|
| Age | 1.01 (0.306) | 1.03 (0.224) | – |
| Male sex | 0.437 (0.011) | 0.275 (0.042) | 0.470 (0.028) |
| African-American ethnicity | 0.290 (0.038) | 0.378 (0.204) | 0.305 (0.047) |
| Education | 0.821 (0.015) | 0.805 (0.079) | 0.801 (0.007) |
| Activity level | 0.971 (0.796) | 0.931 (0.686) | – |
| Heavy smoking (≥40 cigarettes per day during time smoked) | 0.913 (0.901) | 0.977 (0.983) | – |
| DBP (per 20 mm Hg) | 1.03 (0.894) | 2.14 (0.227) | – |
| SBP (per 20 mm Hg) | 1.01 (0.942) | –† | – |
| Drinkers who did not specify their maximum alcohol consumption per day | 4.37 (<0.001) | 4.65 (0.011) | 3.33 (<0.001) |
| History of immobility (>1 day) | 1.55 (0.091) | 2.53 (0.015) | 1.71 (0.043) |
| Family history of first-degree relatives with superficial venous events | 1.54 (0.301) | 1.55 (0.520) | – |
| Family history of first-degree relatives with varicose veins | 2.30 (0.002) | 1.25 (0.706) | 2.02 (0.009) |
| Family history of first-degree relatives with DVE | 1.74 (0.177) | 1.25 (0.637) | – |
*Age variable was adjusted for sex only; and sex variable was adjusted for age only.
†Instead of including both SBP and DBP, we used DBP and the residual of regression of SBP on DBP, so as not to double-count the shared (collinear) contribution by the SBP and DBP values.
DBP, diastolic blood pressure; DVE, deep venous event; OR, odds ratio; SBP, systolic blood pressure; SVT, superficial venous thrombosis.