Cox regression models of 6070 men followed from 1974 to 1977 until event or until 75 years of age
| Strain group | Coronary heart disease | Stroke | ||
|---|---|---|---|---|
| N (N events) | HR (95% CI) | N (N events) | HR (95% CI) | |
| All | 6070 (1052) | 6070 (549) | ||
| Active | 2357 (384) | 1.06 (0.85 to 1.32) | 2357 (208) | 0.91 (0.70 to 1.22) |
| High strain | 671 (131) | 1.31 (1.01 to 1.70) | 671 (64) | 1.05 (0.74 to 1.48) |
| Passive | 2363 (433) | 1.23 (1.00 to 1.53) | 2363 (212) | 0.96 (0.74 to 1.28) |
| Ever-smokers | 4350 (826) | 4350 (406) | ||
| Active | 1650 (277) | 1.00 (0.78 to 1.29) | 1650 (152) | 0.87 (0.64 to 1.20) |
| High strain | 499 (109) | 1.37 (1.02 to 1.83) | 499 (46) | 0.92 (0.62 to 1.38) |
| Passive | 1723 (361) | 1.31 (1.03 to 1.68) | 1723 (158) | 0.90 (0.66 to 1.25) |
| Never-smokers | 1437 (184) | 1437 (113) | ||
| Active | 607 (88) | 1.21 (0.76 to 1.99) | 607 (46) | 1.11 (0.61 to 2.18) |
| High strain | 141 (18) | 1.04 (0.55 to 1.96) | 141 (13) | 1.39 (0.63 to 3.08) |
| Passive | 518 (57) | 0.90 (0.55 to 1.52) | 518 (42) | 1.18 (0.64 to 2.35) |
| Blue-collar workers | 3020 (555) | 3020 (279) | ||
| Active | 41 (7) | 1.04 (0.44 to 2.11) | 41 (5) | 1.30 (0.45 to 2.906) |
| High strain | 492 (101) | 1.36 (1.01 to 184) | 53 (492) | 1.22 (0.82 to 1.82) |
| Passive | 2008 (372) | 1.20 (0.94 to 1.55) | 2008 (75) | 0.93 (0.68 to 1.30) |
| White-collar workers | 3050 (497) | 3050 (270) | ||
| Active | 2316 (377) | 1.14 (0.80 to 1.71) | 2316 (203) | 0.93 (0.60 to 1.54) |
| High strain | 179 (30) | 1.15 (0.69 to 1.92) | 179 (11) | 0.63 (0.29 to 1.30) |
| Passive | 355 (612) | 1.24 (0.80 to 1.95) | 355 (37) | 1.16 (0.68 to 2.06) |
| Self-reported stress at baseline | 2177 (381) | 2177 (201) | ||
| Active | 1014 (170) | 1.01 (0.70 to 1.49) | 1014 (98) | 1.98 (1.09 to 4.05) |
| High strain | 236 (47) | 1.28 (0.82 to 2.02) | 236 (20) | 1.92 (0.92 to 4.28) |
| Passive | 722 (131) | 1.13 (0.78 to 1.69) | 722 (73) | 2.15 (1.17 to 4.44) |
| No self-reported stress at baseline | 3742 (381) | 3742 (330) | ||
| Active | 1304 (203) | 1.00 (0.77 to 1.32) | 1304 (105) | 0.67 (0.49 to 0.94) |
| High strain | 411 (77) | 1.23 (0.89 to 1.70) | 411 (40) | 0.84 (0.56 to 1.26) |
| Passive | 1568 (635) | 1.21 (0.94 to 1.58) | 1568 (131) | 0.72 (0.53 to 1.00) |
| Hypertension at baseline | 1341 (314) | 1341 (201) | ||
| Active | 512 (129) | 1.50 (1.00 to 2.33) | 512 (78) | 0.86 (0.56 to 1.35) |
| High strain | 160 (37) | 1.37 (0.84 to 2.29) | 160 (22) | 0.79 (0.45 to 1.38) |
| Passive | 517 (122) | 1.41 (0.94 to 2.20) | 517 (74) | 0.81 (0.53 to 1.29) |
| No hypertension at baseline | 4715 (736) | 4715 (347) | ||
| Active | 1840 (254) | 0.93 (0.72 to 1.21) | 1840 (129) | 0.96 (0.68 to 1.39) |
| High strain | 509 (94) | 1.30 (0.96 to 1.76) | 509 (42) | 1.21 (0.78 to 1.88) |
| Passive | 1842 (311) | 1.18 (0.93 to 1.53) | 1842 (138) | 1.07 (0.76 to 1.55) |
| Body mass index <30 | 5544 (938) | 5544 (499) | ||
| Active | 2188 (343) | 0.99 (0.79 to 1.25) | 2188 (196) | 0.97 (0.72 to 1.31) |
| High strain | 598 (113) | 1.23 (0.94 to 1.62) | 598 (57) | 1.08 (0.75 to 1.57) |
| Passive | 2150 (387) | 1.18 (0.95 to 1.48) | 2150 (190) | 0.99 (0.74 to 1.34) |
| Body mass index≥30 | 516 (113) | 516 (50) | ||
| Active | 167 (41) | 1.92 (0.98 to 4.21) | 167 (12) | 0.54 (0.23 to 1.33) |
| High strain | 70 (17) | 2.05 (0.93 to 4.81) | 70 (7) | 0.88 (0.31 to 2.35) |
| Passive | 209 (46) | 1.76 (0.90 to 3.84) | 209 (22) | 0.83 (0.40 to 1.91) |
| No diabetes at baseline | 5900 (989) | 5900 (515) | ||
| Active | 2292 (357) | 1.04 (0.84 to 1.31) | 2292 (194) | 0.91 (0.69 to 1.22) |
| High strain | 647 (123) | 1.31 (1.01 to 1.72) | 647 (60) | 1.05 (0.74 to 1.50) |
| Passive | 2299 (411) | 1.24 (1.00 to 1.55) | 2299 (200) | 0.97 (0.73 to 1.30) |
| Diabetes at baseline | 170 (63) | 170 (34) | ||
| Active | 65 (27) | 1.26 (0.56 to 3.39) | 65 (14) | 1.02 (0.36 to 3.59) |
| High strain | 24 (8) | 1.08 (0.37 to 3.28) | 24 (4) | 0.96 (0.23 to 4.09) |
| Passive | 64 (22) | 1.00 (0.43 to 2.73) | 64 (12) | 0.96 (0.33 to 3.43) |
All models are adjusted for age. Low-strain group is used as the reference group in all analyses.